| Title: | Mass-Sensitive Biochemical Microsensors |
| Author: | Brand, Oliver |
| Abstract: | A resonant microsensor platform based on disk-type microstructures vibrating in an in-plane resonance mode for chemical and biochemical sensing applications in gas and liquid environments is presented. Based on measured short-term frequency stabilities of 1.1 10^-8 in air and 2.3 10^-6 in water, mass detection limits in the low femtogram and sub-picogram, respectively, are achieved. In a biosensing application, biomolecules are immobilized on the resonator surface. Upon selective binding of analyte molecules (e.g. via antibody-antigen binding), the mass of the resonator is increased, resulting in a measurable decrease of its resonance frequency. The feasibility of liquid-phase biosensing using the disk resonators is demonstrated experimentally by detecting anti-beta-galactosidase antibody using covalently immobilized beta-galactosidase enzyme. |
| Description: |
Presented on October 10, 2008 from 11am-2pm at the Microelectronics Research Center building on the Georgia Tech campus This talk was part of the fall 2008 meeting of the NANOFANS Forum: Bridging Biology and Nanotechnology Runtime: 31:08 minutes |
| Type: |
Presentation
Video |
| URI: | http://hdl.handle.net/1853/26206 |
| Date: | 2008-10-10 |
| Contributor: |
Georgia Institute of Technology. Microelectronics Research Center
Georgia Institute of Technology. School of Electrical and Computer Engineering |
| Publisher: | Georgia Institute of Technology |
| Subject: |
Sensors
MEMS Biochemical microsensors |
| Files | Size | Format | View | Description |
|---|---|---|---|---|
| brand.mp4 | 86.79Mb | MPEG-4 video |
View/
|
Download Video |
| brand_streaming.html | 917bytes | HTML |
View/
|
Streaming Video |
