Voit *et al.*, *In Silico* Biol. 5, 0010 (2004); Figure 2

Figure 2: According to conventional wisdom of modeling linear pathways, in which X_{1} is converted into X_{2} and then X_{3}, the equation for X_{3} does not include X_{1}, because its effect is indirect. Nonetheless, X_{1} does affect X_{3}, as is shown in the time courses (a) and the phase-plane plots on the right-hand side (b and c). The effect of X_{1} (c) has entirely different characteristics than that exerted by X_{2} (b) and is somewhat less pronounced. (Numerical model used for this example: At time t = 0.1, X_{1} is externally set to 0.05.) |

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