Browsing by Subject "Amyloid"
Now showing items 1-3 of 3
Roles of protein sequence and cell environment in cross-species prion transmission and amyloid interference (Georgia Institute of Technology, 2014-07-08)Proteinaceous infectious particles, termed 'prions' are self-perpetuating protein isoforms that transmit neurodegenerative diseases in mammals and phenotypic traits in yeast. Each conformational variant of a prion protein ...
(Georgia Institute of Technology, 2011-09-28)Polyglutamine-expanded fragments, derived from the human huntingtin protein, are aggregation-prone and toxic in yeast cells, bearing endogenous QN-rich proteins in the aggregated (prion) form. Attachment of the proline-rich ...
(Georgia Institute of Technology, 2009-06-15)