DNA, while best known for its coding abilities, can also be used as a structural material to form nanostructures. DNA nanostructures can be designed with very specific chemistry and structure size and shape, and have the ...

Dendritic cells (DCs) are potent antigen-presenting cells (APCs) that orchestrate an immune response to variety of pathogens or initiate tolerance. Successful manipulation of DCs to control the immune system is a powerful ...

Approximately 1 in 8 women in the United States will be diagnosed with breast cancer. Among these women, 25-30% will have breast cancer where the HER2 gene is overexpressed and human epidermal growth factor receptor 2 ...

The goal of this project is to develop a vehicle for a therapy treatment that increases stem cell-mediated tissue regeneration in bone defects. Tissue engineering has been viewed as a better strategy to repair bone defects ...

Dendritic Cells (DCs) have shown great potential in a variety of immunotherapeutic applications due to their key role in both the innate and adaptive immune response. This study aims to observe the activation and phenotypic ...

This study aims to conduct an in vitro study confirming the affinity of vascular cell adhesion molecule-1 (VCAM-1) specific peptide surface modified superparamagnetic iron oxide nanoparticles (SPIOs) for atherosclerosis ...

Liposomes, spherical nanoparticles composed of phospholipid bilayers, have been suggested as a drug delivery system for potent chemotherapeutics. As the lipid structure transitions from gel to liquid-crystalline the structure ...

Monoclonal antibodies (mAbs) are highly specific antigen binding proteins that are used as biological reagents, therapeutics, and in rapid diagnostics. While mAbs have extensive potential applications, their means production ...

This project focuses on evaluating the effects of nanoparticles on the cellular responses in human oral squamous cell carcinoma (HSC) cells during the administration of cisplatin. Cisplatin is an effective chemotherapeutic ...

Gene regulation through small interfering RNA (siRNA) is a useful way to improve therapeutics and treat diseases. However, since siRNA is rapidly degraded by nucleases in the bloodstream and is anionic and highly hydrophilic, ...