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dc.contributor.authorKottke, Peter
dc.date.accessioned2008-06-25T20:02:45Z
dc.date.available2008-06-25T20:02:45Z
dc.date.issued2008-04-08
dc.identifier.urihttp://hdl.handle.net/1853/23056
dc.descriptionPeter Kottke, a research engineer in the School of Mechanical Engineering presented a lecture at the Nano@Tech Meeting on April 8, 2008 at 12 noon in room 102 of the MiRC buildingen_US
dc.descriptionRuntime: 42:17 minutes
dc.description.abstractPeter Kottke described the SMS probe, a tool currently under development for mass spectrometric imaging of live biological samples in vitro. In order to obtain spatially resolved images of chemical species distributions in vitro, an ion source is needed that samples from a small volume of liquid. The SMS probe is based on a novel approach to electrospray ionization (reverse-Taylor-cone electrospray), which requires a reversal of orientation of conventional electrospray ionization (ESI) sampling. Electrospray ionization mass spectrometry (ESI-MS) has the advantage of providing a means for transferring large biological molecules directly from solution into the gas phase under atmospheric pressure. The unique advantages of the reverse-Taylor-cone ionization concept are the minimum and highly localized (in space) sample volume (i.e., high resolution) that is being probed and, most importantly, its unique suitability for use in scanning probe chemical imaging applications, including imaging biological samples under physiological conditions (i.e., in aqueous solution).en_US
dc.format.extent42:17 minutes
dc.language.isoen_USen_US
dc.publisherGeorgia Institute of Technologyen_US
dc.subjectNanotechnologyen_US
dc.subjectMass spectrometryen_US
dc.subjectSMS probeen_US
dc.subjectReverse-Taylor-cone ionizationen_US
dc.subjectElectrospray ionization
dc.subjectPorous aluminum oxide
dc.titleScanning Mass Spectrometry (SMS) Probeen_US
dc.typeLectureen_US
dc.typeVideo
dc.contributor.corporatenameGeorgia Institute of Technology. School of Mechanical Engineering


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