• The Artificial Pancreas 

  Klonoff, David (Georgia Institute of Technology, 2011-04-07)

  An artificial pancreas is an engineered device for treating diabetes, which is one of the greatest epidemic diseases in the US and worldwide. In the US 105 million people have diabetes or prediabetes. An artificial pancreas ...

• Enhancing Solute Transport in Immature Cartilage and Engineered Tissue Constructs 

  Ateshian, Gerard A. (Georgia Institute of Technology, 2011-03-08)

  Osteoarthritis (OA) is a debilitating degenerative disease that afflicts an estimated 27 million Americans age 25 and older. This disease leads to the progressive degradation of the articular layers of diarthrodial joints, ...

• Functional molecular imaging in the brain 

  Jasanoff, Alan (Georgia Institute of Technology, 2011-02-24)

  Functional magnetic resonance imaging (fMRI) with contrast agents sensitive to neural activity could have great impact in neuroscience by combining noninvasive whole-brain coverage with molecular-level specificity for ...

• Homogeneity tests among groups for microsatellite data 

  Pinheiro, Hildete Prisco (Georgia Institute of Technology, 2011-01-27)

  We propose a homogeneity test among groups on a quadratic distance measure. The underlying mutation process in the microsatellite loci is studied using the stepwise mutation model. Asymptotic normality of the test statistic ...

• Design Principles for Cytokine-Neutralizing Polymers 

  Washburn, Newell R. (Georgia Institute of Technology, 2009-11-19)

• EGFR Family Gymnastics 

  Griffith, Linda G. (Georgia Institute of Technology, 2009-10-22)

• Smart Biomaterials Inspired by Nature's Mechanisms 

  Murphy, William L. (Georgia Institute of Technology, 2009-10-29)

  Control over the soluble signals that cells encounter in their local environment is a common theme in natural tissue formation, and also an emerging theme in functional tissue engineering strategies. This concept is ...

• Scalable Manufacture of Cells 

  Rao, Mahendra S. (Georgia Institute of Technology, 2009-09-10)

  Preparing cells for therapy requires developing a scalable GMP'able model for cell culture for the undifferentiated cells and for the differentiated cells derived from them. It is also important to develop testing processes ...

• Cell Transplantation for Myocardial Repair: Are We Ready for Prime Time? 

  Taylor, Doris A. (Georgia Institute of Technology, 2001-08-06)

• The Nanoscale Biointerface and Healing Biomaterials 

  Ratner, Buddy D. (Georgia Institute of Technology, 2002-10-03)

  Implantable medical devices, and the biomaterials that comprise them, are measured on macro scales (centimeters). Yet the biocompatibility of such devices may be dictated by phenomena best described at nanometer dimensions. ...

• Stem cell biology and the oxygen environment 

  Csete, Marie (Georgia Institute of Technology, 2003-03-18)

  Traditional cell cultivation in labs is conducted in an environment of 20% O2 (basically room air), though the mean oxygen tension at the tissue level in adults is about 3%. Our work suggests that stem cell growth, death, ...

• Pathogenesis of Atherosclerosis: Redox Signaling as a Unifying Theme 

  Alexander, R. Wayne (Georgia Institute of Technology, 2003-01-30)

• MRI of carotid atherosclerosis 

  Yuan, Chun (Georgia Institute of Technology, 2003-03-20)

  Atherosclerotic disease of the carotid bifurcation is a major source of thrombo-embolism and subsequent stroke. Non-invasive in vivo investigations of the relationship between atherosclerotic plaque tissue composition/morphology ...

• Adult Mesenchymal Stem Cell Therapy in Joint Injury and Disease 

  Barry, Frank (Georgia Institute of Technology, 2002-10-08)

  Frank Barry is the Director of Arthritis Research at Osiris Therapeutics, Inc., a leading stem cell therapeutic company focused on developing and marketing products to treat medical conditions in the inflammatory, orthopedic, ...

• Rationale and Methods for a Bio-Engineered Recellularized Heart Valve Based on Decellularized Allograft Tissue Scaffolds 

  Hopkins, Richard A. (Georgia Institute of Technology, 2003-10-14)

  Human allograft transplants offer significant advantages over manufactured mechanical or xenograft tissue valves for many surgical reconstructions. Disadvantages of current generation human valve transplants include: 1.) ...

• Biomolecular Materials That Talk and Listen 

  Stayton, Patrick S. (Georgia Institute of Technology, 2002-10-10)

  "Smart" or "intelligent" materials are those that reversibly change their structural and functional properties in response to environmental signals such as a change in temperature. Nature has itself perfected smart polymers ...

• Bio-inspired Engineering of Biomaterials: Challenges and Opportunities 

  Wang, Chun (Georgia Institute of Technology, 2003-03-27)

• Platform Technologies: Targeted delivery of Imaging Contrast Agents and Chemotherapeutic Drugs 

  Annapragada, Ananth (Georgia Institute of Technology, 2003-03-11)

• Single molecule studies of membrane structure in live cells 

  Ritchie, Ken (Georgia Institute of Technology, 2004-02-19)

  Interactions between a cell and its environment must be transmitted through its plasma membrane. As such, the membrane must have mechanisms to control the localization and interactions of its constituent proteins. I will ...

• Protein Surface Interactions: Role in Biocompatibility 

  Brash, John L. (Georgia Institute of Technology, 2004-01-22)

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