Department of Biomedical Engineering Undergraduate Research Option Theses
The Research Option offers students majoring in biomedical engineering the opportunity for a substantial, in-depth research experience. Students are strongly encouraged at the end of their experience to work with their faculty mentor to develop a journal publication or conference presentation on the research in addition to the actual thesis.
All materials in SMARTech are protected under U.S. Copyright Law and all rights are reserved. Such materials may be used, quoted or reproduced for educational purposes only with prior permission, provided proper attribution is given. Any redistribution, reproduction or use of the materials, in whole or in part, is prohibited without prior permission of the author.
Recent Submissions
-
Effects of Microgravity on Visual Impairment and Intracranial Pressure Syndrome
(Georgia Institute of Technology, 2019-02-12)Studying the effects of microgravity on visual impairment and intracranial pressure syndrome. Specifically looking at the combined effects of mechanical stretch and homocysteine. -
Material-Directed Chondrogenic Differentiation Under Mechanical Stimulation
The mechanical properties of scaffolds used to encapsulate stem cells are widely known to help direct the differentiation of those stem cells down different lineages. When studying chondrogenesis, the ability of the scaffold ... -
Exosome-mediated differentiation of adipose-derived mesenchymal stem cells to trabecular meshwork cells
Glaucoma is the second leading cause of blindness and affects over 70 million people worldwide. Intraocular pressure (IOP), a well-established risk factor for primary open angle glaucoma, the most common form of glaucoma, ... -
An examination of the noninflammatory role of astrocytes in glutamate excitotoxicity in SOD1 G93A ALS mouse model
Astrocytes can be found between the vascular and neuronal elements of the central nervous system, where they take up and release molecules in order to maintain a homeostatic microenvironment for optimal neuron growth. ... -
A Biophysical Model of Endothelial Cell Behavior during Cerebral Cavernous Malformation
Cerebral Cavernous Malformations (CCMs) are a collection of enlarged blood vessels with irregular structure in the brain that are caused by a mutation in one of three genes, CCM-1, -2, or -3. For those with CCMs, the ... -
Multi-scale Quantitative Assessment of Apoptosis, Bioenergetics, and Oxidative Stress Molecular Mechanisms in the SOD1 G93A Transgenic ALS Mouse Model
Apoptosis, bioenergetics, and oxidative stress have been implicated in Amyotrophic Lateral Sclerosis (ALS) disease progression; it is unclear as to how the interactions within this highly inter-related triad of categories ... -
Modeling Electrophysiological Dynamics in Transient Deep Brain Stimulation of the Subcallosal Cingulate
Deep brain stimulation (DBS) is a promising investigational treatment for patients with treatment resistant depression (TRD). However, the exact mechanism of action of SCCwm-DBS is unknown and its effects on the electrophysiology ... -
Characterization of Electrodes for Kilohertz Electrical Stimulation
Kilohertz electrical stimulation (KES) induces repeatable and reversible conduction block of nerve activity and is a potential therapeutic option for various diseases and disorders resulting from pathological or undesired ... -
A preliminary study comparing challenging standing and walking balance tasks to discriminate between experts and novices
There are no established techniques to reliably discriminate between groups of healthy individuals based on balance skill. Current balance assessment techniques often fail to detect subtle differences in balance skill, ... -
Hydrogels with magnetic nanoparticles and fluorescent component
The goal of this project is to develop a vehicle for a therapy treatment that increases stem cell-mediated tissue regeneration in bone defects. Tissue engineering has been viewed as a better strategy to repair bone defects ... -
Time Course of Adaptation to a Split-Crank Ergometer
Cycling ergometers have been used in rehabilitation as a way to increase the symmetry in lower limb force output. Adaptation and savings, a property of memory that is characterized by a faster rate of relearning than the ... -
The Effect of Combined Physical and Mental Exertion Prior to using DETECT, a Novel Neuropsychological Test Battery
The purpose of this intervention study is to identify the effect of physical and mental exertion on neuropsychological assessments using the neuropsychological DETECT test in healthy, moderately fit, college-aged students. ... -
Potential therapy against Glioblastoma using Motile Nanocarrier Expressing TRAIL and Azurin
Glioblastoma (GBM) is the most common and aggressive type of gliomas in humans. It is also highly resistant to most treatment methods. Nearly 12,000 people are diagnosed with glioblastoma each year in the United States. ... -
Development of a coronary flow model for aortic valve testing
Transcatheter aortic valve replacement is a promising new technique to treat patients with severe aortic stenosis due to its minimally invasive approach. Unfortunately, higher levels of thrombosis from utilizing this device ... -
Investigation of immunomodulation on myofibroblast activation: Implications for fibrotic development in wound healing
(Georgia Institute of Technology, 2017-05-03)Endogenous mechanisms of wound healing and remodeling are a particularly attractive avenue for targeting traumatic injury and incomplete growth. Macrophages are highly involved in this process, and generally exhibit either ... -
MRI-Based Investigation into the Effects of Simulated Microgravity on Cerebrospinal Fluid and Vascular Flow
National Aeronautics and Space Administration (NASA) astronauts have reported decrease in visual acuity due to Microgravity Ocular Syndrome (MOS) after returning from long duration space missions. It is hypothesized that ... -
Towards Passive Unlabeled Cell Sorting in a Microfluidic Flow Chamber
Cell separation is utilized for a variety of purposes in biomedicine, including clinical diagnosis, or batch purification or rare cell isolation within a research laboratory setting. The currently used methods for cell ... -
Mechanically Activated Currents in Mechanosensitive Cells
The purpose of this study is to analyze the effect of ultrasonic pressure on the mechanosensitive channel activity in the N2A cell line. Prior research has indicated that certain ion channels in the cellular membrane of ... -
Inflammatory CD8+ T Cells Are Reduced by Applying FTY-720 to Activate Sphingosine-1-Phosphate Receptor Signaling
Biomaterials generally induce a natural inflammatory response which can be altered by adding molecules to influence immune cell recruitment. Sphingosine-1-phosphatase (S1P) is a biological signaling lipid which performs ... -
Development of an EPIC-μCT imaging method for analyzing proteoglycan content in neocartilage constructs for the use in osteoarthritis therapeutics
Osteoarthritis (OA), characterized by debilitating joint pain, is a degenerative disease caused by the breakdown of cartilage in joints and adjacent bone. It is the most common type of arthritis, affecting 10-12% of the ...
RSS 1.0