Department of Biomedical Engineering Undergraduate Research Option Theses
The Research Option offers students majoring in biomedical engineering the opportunity for a substantial, in-depth research experience. Students are strongly encouraged at the end of their experience to work with their faculty mentor to develop a journal publication or conference presentation on the research in addition to the actual thesis.
All materials in SMARTech are protected under U.S. Copyright Law and all rights are reserved. Such materials may be used, quoted or reproduced for educational purposes only with prior permission, provided proper attribution is given. Any redistribution, reproduction or use of the materials, in whole or in part, is prohibited without prior permission of the author.
Recent Submissions
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Development of a collagen-based model for testing nanoparticle drug delivery to tumors
(Georgia Institute of Technology, 2016-07-18)Cancer continues to take many lives each year and has posed a seemingly insurmountable challenge to scientists around the world. Traditional methods of treatment, including chemotherapy, are ineffective and result in ... -
Evaluating Activity and Sleep Tracking Technologies for Older Adults
(Georgia Institute of Technology, 2016-07-18)There are currently over 99 million citizens in the United States who are age 50 and older. Many of these older adults are interested in independently maintaining their mental and physical well-being. There are various ... -
Reducing Delay Time in Hand Mentor Pro to Improve Clinical Functionality
(Georgia Institute of Technology, 2016-07-18)Stroke is third leading cause of disability worldwide, and the burden of stroke across the world is steadily growing. However, it is the leading cause of disability in the United States. Each year, 800,000 people in the ... -
Small Animal Model of Osteochondritis Dissecans
(Georgia Institute of Technology, 2016-07-18)Juvenile Osteochondritis Dissecans (JOCD) is a joint disorder that predominantly affects athletic children and adolescents. It is characterized by the formation of osteochondral loose bodies which cause pain and swelling ... -
Effect of Incorporation of lysolipid on the Stability of Dipalmitoyl Phosphatidylcholine Bilayer Membrane: Molecular Dynamics Simulation Approach
(Georgia Institute of Technology, 2016-07-18)Previous studies have found that incorporating monopalmitoylphosphatidylcholine(MPPC) lysolipids into PEGylated dipalmitoylphosphatidylcholines(DPPC) membranes of conventional thermosensitive liposomes lowers their phase ... -
Assessing the Stiffness of the Achilles tendon using Laser Doppler Vibrometry
(Georgia Institute of Technology, 2016-07-18)There were approximately 232,000 Achilles tendon sports injuries in the United States for individuals six and over. The reasons for injuries are weak blood supply to the Achilles tendon and bowstring effect due to ankle ... -
A Comparative Study Between Fetal and Calf Bovine Pericardium
(Georgia Institute of Technology, 2016-07-18)There is a need of a lower profile device of transcatheter heart valves. One way to simply achieve this task is to decrease the size of the device by using a thinner bovine pericardium. The devices currently use calf ... -
Degradation of dental resin through water diffusion
(Georgia Institute of Technology, 2016-07-18)Dental resin is used in the dentistry field as restorative material that fills out cavity of teeth. It is insoluble, aesthetic, unreactive in dehydration, and inexpensive which makes it a very reasonable option for patients ... -
A Molecular Dynamics SImulation of Norepinephrine Metabolites on Amyoid-Beta Proteins
(Georgia Institute of Technology, 2016-07-18)The cause of Alzheimer’s disease are the deposits of Amyloid-Beta (Aβ) protein fragments and the twisted fibers of tau proteins. These proteins build up inside the brain inducing the destruction and death of nerve cells ... -
The Effect of 3,4-Dihydroxymandelic Acid and Normetanephrine on Amyloid-beta 40 Monomer Aggregation in Alzheimer's Disease Using Molecular Modeling
(Georgia Institute of Technology, 2016-07-18)Alzheimer’s disease is the one of the most common types of degenerative dementia. It is known to cause memory loss and loss of other intellectual abilities. The formation of neurotoxic plaque composed of amyloid beta ... -
Development of a Phase-amplitude Coupling Toolbox for Assessing Changes in Cross-frequency Coupling Due to Deep Brain Stimulation Therapies for Treatment Resistant Depression
(Georgia Institute of Technology, 2016-07-18)Phase-amplitude coupling (PAC) is theorized to play a fundamental physiological role in neuronal oscillations of the brain. This work contends that changes in PAC due to deep brain stimulation (DBS) in treatment-resistant ... -
Computational Study on the Effects of Halogenated Compounds on Amyloid-Beta 40 Monomer Aggregation in Alzheimer's Disease
(Georgia Institute of Technology, 2016-07-18)Alzheimer’s disease (AD) is one of the most common types of degenerative dementia. Investigation into the mechanism of aggregation of the most potential Alzheimer’s protein, amyloid-beta (Aβ40) peptide suggested that the ... -
Molecular Dynamics Simulation of Mixed Lipid Bilayer with DPPC and MPPC: Effect of Configurations in Gel-phase.
(Georgia Institute of Technology, 2016-01-25)Liposomes, spherical nanoparticles composed of phospholipid bilayers, have been suggested as a drug delivery system for potent chemotherapeutics. As the lipid structure transitions from gel to liquid-crystalline the structure ... -
Effects of HIV-1 Infection on Bone Growth in HIV-1 Transgenic Rats
(Georgia Institute of Technology, 2016-01-25)Human immunodeficiency virus (HIV) is a subgroup of a retrovirus that causes acquired immunodeficiency syndrome (AIDS), which is a progressive failure of the immune system. Millions of dollars have been donated for the ... -
Type I versus type II cytokine levels as a function of SOD1 G93A mouse amyotrophic lateral sclerosis disease progression
(Georgia Institute of Technology, 2016-01-25)Amyotrophic Lateral Sclerosis (ALS) is a fatal motoneuron disease that is characterized by the degradation of neurons throughout the central nervous system. Inflammation have been cited a key contributor to ALS neurodegeneration, ... -
Engineering three dimensional cardiospheres from pluripotent stem cells
(Georgia Institute of Technology, 2016-01-25)Previously, we have shown that generating 3D cardiospheres from pre-differentiated cardiomyocytes derived from human pluripotent stem cells has enriched and matured the cardiomyocyte populations compared to the 2D controls. ... -
Comparison of craniotomy versus craniectomy methods for studying intracranial pressure increases in rats for traumatic brain injury models
(Georgia Institute of Technology, 2014-05-02)Traumatic brain injury (TBI) is the leading cause of death for people under the age of 45 (Gabrielian et al, 2011). One of the most troubling problems for physicians in treating TBI is increased intracranial pressure (ICP). ... -
Microfluidic Stiffness-Dependent Separation of Red Blood Cells for Early Malaria Diagnosis and Surveillance
(Georgia Institute of Technology, 2013-12-13)The characterization of the mechanical properties of cells has many broad applications since cell elasticity can indicate pathological state. Notably, many diseases cause significant changes in mechanical properties; for ... -
Mobile Medical App for Remote Screening of Appendicitis
(Georgia Institute of Technology, 2015-08-18)This study aimed to identify the possibility of using the sensors found in mobile devices as tools for remotely diagnosing or assessing the risk of appendicitis. The study was performed by created a mobile application on ... -
Animal Model of Mild Traumatic Brain Injury: An Assessment of Impact Location
(Georgia Institute of Technology, 2015-08-18)With a high prevalence of mild traumatic brain injuries that occur in sports today, more research is needed in order to reveal the biomechanics behind these devastating and often life-changing injuries. At the professional ...
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