A novel method for pulmonary emboli visualization from high-resolution CT images

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Please use this identifier to cite or link to this item: http://hdl.handle.net/1853/31215

Title: A novel method for pulmonary emboli visualization from high-resolution CT images
Author: Pichon, Eric ; Novak, Carol L. ; Kiraly, Atilla P. ; Naidich, David P.
Abstract: Pulmonary Embolism (PE) is one of the most common causes of unexpected death in the US. The recent introduction of 16-slice Computed Tomography (CT) machines allows the acquisition of very high-resolution datasets. This has made CT a more attractive means for diagnosing PE, especially for previously difficult to identify small subsegmental peripheral emboli. However, the large size of these datasets makes it desirable to have an automated method to help radiologists focus directly on potential candidates that might otherwise be overlooked. We propose a novel method to highlight potential PEs on a 3D representation of the pulmonary arterial tree. First lung vessels are segmented using mathematical morphology techniques. The density values inside the vessels are then used to color the outside of a Shaded Surface Display (SSD) of the vessel tree. As PEs are clots of significantly lower Hounsfield Unit (HU) values than surrounding contrast-enhanced blood, they appear as salient contrasted patches in this 3D rendering. During preliminary testing on 6 datasets 19 PEs out of 22 were detected (sensitivity 86%) with 2 false positives for every true positive (Positive Predictive Value 33%).
Description: ©2004 SPIE--The International Society for Optical Engineering. One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited. The electronic version of this article is the complete one and can be found online at: DOI Link: http://dx.doi.org/10.1117/12.532892 Presented at Medical Imaging 2004: Visualization, Image-Guided Procedures, and Display,: 15 February 2004, San Diego, California, USA. DOI: 10.1117/12.532892
Type: Proceedings
URI: http://hdl.handle.net/1853/31215
ISSN: 1605-7422
Citation: Eric Pichon, Carol L. Novak, Atilla P. Kiraly, David P. Naidich, “A novel method for pulmonary emboli visualization from high-resolution CT images,” Medical Imaging 2004: Visualization, Image-Guided Procedures, and Display, edited by Robert L. Galloway, Jr., Proceedings of SPIE Vol. 5367, 1605-7422 (2004)
Date: 2004-02-15
Contributor: Siemens Corporate Research
New York University. Medical Center. Dept. of Radiology
Georgia Institute of Technology. School of Electrical and Computer Engineering
Publisher: Georgia Institute of Technology
Society of Photo-Optical Instrumentation Engineers
Subject: Pulmonary embolism
Computed tomography

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