Integrative systems biology is the multidisciplinary and interdisciplinary science that studies complex biological systems as integrated functioning entities at multiple levels. It generates data through discovery-driven high-throughput experiments, integrates these with biological information from hypothesis-driven experiments, creates new devices and techniques for elucidating biological systems, analyzes experimental results with methods of mathematics, physics, and computer science, and uses insights from these multi-disciplinary investigations for the manipulation and optimization of biological systems.

The Integrative BioSystems Institute (IBSI) at Georgia Tech fosters collaboration among the Colleges of Science, Engineering, and Computer Science by providing a physical and intellectual focus for integrative, interdisciplinary and multidisciplinary research in the quantitative life sciences.

Collections in this community

Recent Submissions

  • Switches and Latches: New Elements in the Control of Mitosis 

    Hunt, Tim (Georgia Institute of Technology, 2011-05-04)
    The process of mitosis involves a comprehensive reorganization of the cell: chromosomes condense, the nuclear envelope breaks down, the mitotic spindle is assembled, cells round up and release their ties to the substrate ...
  • Evolutionary insights into the control of drug specificity 

    Fernandez, Ariel (Georgia Institute of Technology, 2010-11-10)
    We shall present on research endeavors focusing on controlling specificity in molecularly targeted anticancer therapy. A basic goal is to reduce toxic side effects by structure-based drug design exploiting our understanding ...
  • The Genomics of Restriction and Modification 

    Roberts, Richard J. (Georgia Institute of Technology, 2010-10-13)
    The discovery of new restriction enzymes has progressed from the slow and laborious process of examining individual bacterial strains experimentally to the much higher through-put that can be obtained using bioinformatics ...
  • Cell Cycle Control 

    Nurse, Paul (Georgia Institute of Technology, 2010-09-08)
    The growth and reproduction of all living organisms are dependent on the cell cycle, the process which leads to cell division. Uncontrolled division of cells is important for disease particularly cancer. Two events, S-phase ...