Homogeneity tests among groups for microsatellite data

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dc.contributor.author Pinheiro, Hildete Prisco
dc.date.accessioned 2011-02-03T17:39:54Z
dc.date.available 2011-02-03T17:39:54Z
dc.date.issued 2011-01-27
dc.identifier.uri http://hdl.handle.net/1853/36808
dc.description Hildete Pinheiro of the University of Campinas, Brazil presented a lecture on January 27, 2011 from 11:00 AM to 12:00 PM in the IBB building, room 1107. en
dc.description Runtime: 33:43 minutes en
dc.description.abstract We propose a homogeneity test among groups on a quadratic distance measure. The underlying mutation process in the microsatellite loci is studied using the stepwise mutation model. Asymptotic normality of the test statistic is proven under very mild regularity conditions. Resampling methods, such as jackknife, are used in the application to build confidence intervals for the difference in allelic variation between and within groups. The method is applied in a real data to test whether there are differences in the distribution of the repeated sequence among groups defined by ethnicity and alcoholism index (ALDX1). en
dc.format.extent 33:43 minutes
dc.language.iso en_US en
dc.publisher Georgia Institute of Technology en
dc.subject Asymptotic theory en
dc.subject Discrete data en
dc.subject Homogeneity test en
dc.subject Jackknife en
dc.subject U-statistics en
dc.subject Statistical genetics en
dc.subject Stepwise mutation en
dc.title Homogeneity tests among groups for microsatellite data en
dc.type Lecture en
dc.type Video en
dc.contributor.corporatename Georgia Institute of Technology. Institute for Bioengineering and Bioscience
dc.contributor.corporatename Universidade Estadual de Campinas


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