| dc.contributor.author | Fleischer, Candace C. | |
| dc.date.accessioned | 2013-01-23T19:55:20Z | |
| dc.date.available | 2013-01-23T19:55:20Z | |
| dc.date.issued | 2012-12-11 | |
| dc.identifier.uri | http://hdl.handle.net/1853/45987 | |
| dc.description | Candace C. Fleischer presented a lecture at the Nano@Tech Meeting on December 11, 2012 at 12 noon in room 1116 of the Marcus Nanotechnology Building. | en_US |
| dc.description | Candace C. Fleischer is a 3rd year Ph.D. candidate in Chemistry (Research Advisor: Christine Payne). She obtained her
B.S. and M.S. degrees in Chemistry from Western Washington University. | |
| dc.description | Runtime: 27:00 minutes | |
| dc.description.abstract | Nanoparticles used in biomedical applications are exposed to a host of extracellular proteins that
can non-specifically adsorb to the nanoparticle surface. We have studied how blood serum proteins can
direct the cellular binding of nanoparticles. We have determined that cationic nanoparticle binding is
increased in the presence of serum proteins, and binding occurs to a scavenger receptor on the cell surface. In
comparison, the cellular binding of anionic nanoparticles is inhibited by serum proteins and the nanoparticle
binds to native protein receptors. | en_US |
| dc.format.extent | 27:00 minutes | |
| dc.language.iso | en_US | en_US |
| dc.publisher | Georgia Institute of Technology | en_US |
| dc.subject | Cellular binding | en_US |
| dc.subject | Nanoparticle | en_US |
| dc.subject | Nanotechnology | en_US |
| dc.subject | Serum protein | en_US |
| dc.title | Nanoparticle Surface Charge Directs the Cellular Binding of Nanoparticle-protein Complexes | en_US |
| dc.type | Lecture | en_US |
| dc.type | Video | en_US |
| dc.contributor.corporatename | Georgia Institute of Technology. Microelectronics Research Center | en_US |
| dc.contributor.corporatename | Georgia Institute of Technology. Nanotechnology Research Center | en_US |
| dc.contributor.corporatename | Georgia Institute of Technology. School of Chemistry and Biochemistry | en_US |
| dc.embargo.terms | null | en_US |
