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dc.contributor.authorFleischer, Candace C.
dc.date.accessioned2013-01-23T19:55:20Z
dc.date.available2013-01-23T19:55:20Z
dc.date.issued2012-12-11
dc.identifier.urihttp://hdl.handle.net/1853/45987
dc.descriptionCandace C. Fleischer presented a lecture at the Nano@Tech Meeting on December 11, 2012 at 12 noon in room 1116 of the Marcus Nanotechnology Building.en_US
dc.descriptionCandace C. Fleischer is a 3rd year Ph.D. candidate in Chemistry (Research Advisor: Christine Payne). She obtained her B.S. and M.S. degrees in Chemistry from Western Washington University.
dc.descriptionRuntime: 27:00 minutes
dc.description.abstractNanoparticles used in biomedical applications are exposed to a host of extracellular proteins that can non-specifically adsorb to the nanoparticle surface. We have studied how blood serum proteins can direct the cellular binding of nanoparticles. We have determined that cationic nanoparticle binding is increased in the presence of serum proteins, and binding occurs to a scavenger receptor on the cell surface. In comparison, the cellular binding of anionic nanoparticles is inhibited by serum proteins and the nanoparticle binds to native protein receptors.en_US
dc.format.extent27:00 minutes
dc.language.isoen_USen_US
dc.publisherGeorgia Institute of Technologyen_US
dc.subjectCellular bindingen_US
dc.subjectNanoparticleen_US
dc.subjectNanotechnologyen_US
dc.subjectSerum proteinen_US
dc.titleNanoparticle Surface Charge Directs the Cellular Binding of Nanoparticle-protein Complexesen_US
dc.typeLectureen_US
dc.typeVideoen_US
dc.contributor.corporatenameGeorgia Institute of Technology. Microelectronics Research Centeren_US
dc.contributor.corporatenameGeorgia Institute of Technology. Nanotechnology Research Centeren_US
dc.contributor.corporatenameGeorgia Institute of Technology. School of Chemistry and Biochemistryen_US
dc.embargo.termsnullen_US


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