Browsing Georgia Tech Theses and Dissertations by Subject "N-(4-Hydroxyphenyl) retinamide"
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Fenretinide increases dihydroceramide and dihydrosphingolipids due to inhibition of dihydroceramide desaturase. (Georgia Institute of Technology, 2006-07-11)N-(4-Hydroxyphenyl) retinamide (4-HPR) is a derivative of all-trans-retinoic acid that induces apoptosis in cancer cell lines and is being tested in clinical trials as a relatively non-toxic anti-cancer agent. 4-HPR induces ...