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dc.contributor.authorLeontis, Neocles B.en_US
dc.contributor.authorAltman, Russ B.en_US
dc.contributor.authorBerman, Helen M.en_US
dc.contributor.authorBrenner, Steven E.en_US
dc.contributor.authorBrown, James W.en_US
dc.contributor.authorEngelke, David R.en_US
dc.contributor.authorHarvey, Stephen C.en_US
dc.contributor.authorHolbrook, Stephen R.en_US
dc.contributor.authorJossinet, Fabriceen_US
dc.contributor.authorLewis, Suzanna E.en_US
dc.contributor.authorMajor, Françoisen_US
dc.contributor.authorMathews, David H.en_US
dc.contributor.authorRichardson, Jane S.en_US
dc.contributor.authorWilliamson, James R.en_US
dc.contributor.authorWesthof, Ericen_US
dc.date.accessioned2013-10-07T18:55:26Z
dc.date.available2013-10-07T18:55:26Z
dc.date.issued2006-04
dc.identifier.citationNeocles B. Leontis, Russ B. Altman, Helen M. Berman, Steven E. Brenner, James W. Brown, David R. Engelke, Stephen C. Harvey, Stephen R. Holbrook, Fabrice Jossinet, Suzanna E. Lewis, François Major, David H. Mathews, Jane S. Richardson, James R. Williamson, and Eric Westhof, “The RNA Ontology Consortium: An open invitation to the RNA community,” RNA 2006. 12: 533-541.en_US
dc.identifier.issn1355-8382
dc.identifier.urihttp://hdl.handle.net/1853/49185
dc.description©2006 RNA Society. Published by Cold Spring Harbor Laboratoryen_US
dc.descriptionDOI: 10.1261/rna.2343206en_US
dc.description.abstractThe aim of the RNA Ontology Consortium (ROC) is to create an integrated conceptual framework—an RNA Ontology (RO)—with a common, dynamic, controlled, and structured vocabulary to describe and characterize RNA sequences, secondary structures, three-dimensional structures, and dynamics pertaining to RNA function. The RO should produce tools for clear communication about RNA structure and function for multiple uses, including the integration of RNA electronic resources into the Semantic Web. These tools should allow the accurate description in computer-interpretable form of the coupling between RNA architecture, function, and evolution. The purposes for creating the RO are, therefore, (1) to integrate sequence and structural databases; (2) to allow different computational tools to interoperate; (3) to create powerful software tools that bring advanced computational methods to the bench scientist; and (4) to facilitate precise searches for all relevant information pertaining to RNA. For example, one initial objective of the ROC is to define, identify, and classify RNA structural motifs described in the literature or appearing in databases and to agree on a computer-interpretable definition for each of these motifs. To achieve these aims, the ROC will foster communication and promote collaboration among RNA scientists by coordinating frequent face-to-face workshops to discuss, debate, and resolve difficult conceptual issues. These meeting opportunities will create new directions at various levels of RNA research. The ROC will work closely with the PDB/NDB structural databases and the Gene, Sequence, and Open Biomedical Ontology Consortia to integrate the RO with existing biological ontologies to extend existing content while maintaining interoperability.en_US
dc.language.isoen_USen_US
dc.publisherGeorgia Institute of Technologyen_US
dc.subjectBiological ontologyen_US
dc.subjectRNAen_US
dc.subjectsequence alignmentsen_US
dc.subject3D structureen_US
dc.subjectRNA motifsen_US
dc.titleThe RNA Ontology Consortium: An Open Invitation to the RNA Communityen_US
dc.typeArticleen_US
dc.contributor.corporatenameBowling Green State University. Dept. of Chemistryen_US
dc.contributor.corporatenameBowling Green State University. Center for Biomolecular Sciencesen_US
dc.contributor.corporatenameStanford University. Medical Centeren_US
dc.contributor.corporatenameStanford University. Medical Informaticsen_US
dc.contributor.corporatenameRutgers University. Dept. of Chemistry and Chemical Biologyen_US
dc.contributor.corporatenameUniversity of California, Berkeley. Dept. of Plant and Microbial Biologyen_US
dc.contributor.corporatenameNorth Carolina State University. Dept. of Microbiologyen_US
dc.contributor.corporatenameUniversity of Michigan. Dept. of Biological Chemistryen_US
dc.contributor.corporatenameGeorgia Institute of Technology. School of Biologyen_US
dc.contributor.corporatenameLawrence Berkeley National Laboratory. Dept. of Structural Biologyen_US
dc.contributor.corporatenameUniversity of California, Berkeley. Dept. of Molecular and Cell Biologyen_US
dc.contributor.corporatenameUniversité de Montréal. Département d’Informatique et de Recherche Opérationnelleen_US
dc.contributor.corporatenameUniversity of Rochester. Medical Centeren_US
dc.contributor.corporatenameDuke University. Dept. of Biochemistryen_US
dc.contributor.corporatenameUniversité Louis Pasteur de Strasbourg Ien_US
dc.contributor.corporatenameInstitut de biologie moléculaire et cellulaireen_US
dc.publisher.originalCold Spring Harbor Laboratory Pressen_US
dc.identifier.doi10.1261/rna.2343206


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