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dc.contributor.advisorRahnema, Farzad
dc.contributor.authorHayward, Robert M.
dc.date.accessioned2014-05-28T21:02:12Z
dc.date.available2014-05-28T21:02:12Z
dc.date.issued2013-04-09
dc.identifier.urihttp://hdl.handle.net/1853/51928
dc.description.abstractA hybrid stochastic-deterministic method, COMET-PE, is developed for dose calculation in radiotherapy. Fast, accurate dose calculation is a key component of successful radiotherapy treatment. To calculate dose, COMET-PE solves the coupled Boltzmann Transport Equations for photons and electrons. The method uses a deterministic iteration to compose response functions that are pre-computed using Monte Carlo. Thus, COMET-PE takes advantage of Monte Carlo physics without incurring the computational costs typically required for statistical convergence. This work extends the method to 3-D problems with realistic source distributions. Additionally, the performance of the deterministic solver is improved, taking advantage of both shared-memory and distributed-memory parallelism to enhance efficiency. To verify the method’s accuracy, it is compared with the DOSXYZnrc (Monte Carlo) method using three different benchmark problems: a heterogeneous slab phantom, a water phantom, and a CT-based lung phantom. For the slab phantom, all errors are less than 1.5% of the maximum dose or less than 3% of local dose. For both the water phantom and the lung phantom, over 97% of voxels receiving greater than 10% of the maximum dose pass a 2% (relative error) / 2 mm (distance-to-agreement) test. Timing comparisons show that COMET-PE is roughly 10-30 times faster than DOSXYZnrc. Thus, the new method provides a fast, accurate alternative to Monte Carlo for dose calculation in radiotherapy treatment planning.en_US
dc.language.isoen_USen_US
dc.publisherGeorgia Institute of Technologyen_US
dc.subjectMonte Carloen_US
dc.subjectTreatment planningen_US
dc.subjectTransport theoryen_US
dc.subject.lcshRadiotherapy
dc.subject.lcshRadiation Dosage
dc.subject.lcshMonte Carlo method
dc.subject.lcshMedical physics
dc.titleA coarse mesh transport method for photons and electrons in 3-Den_US
dc.typeDissertationen_US
dc.description.degreePh.D.
dc.contributor.departmentMechanical Engineering
dc.embargo.termsnullen_US
thesis.degree.levelDoctoral
dc.contributor.committeeMemberElder, Eric
dc.contributor.committeeMemberMorely, Thomas
dc.contributor.committeeMemberWang, Chris K.
dc.contributor.committeeMemberZhang, Dingkang


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