• Login
    View Item 
    •   SMARTech Home
    • Undergraduate Research Opportunities Program (UROP)
    • Undergraduate Research Option Theses
    • View Item
    •   SMARTech Home
    • Undergraduate Research Opportunities Program (UROP)
    • Undergraduate Research Option Theses
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    A Molecular Dynamics SImulation of Norepinephrine Metabolites on Amyoid-Beta Proteins

    Thumbnail
    View/Open
    SHIN-UNDERGRADUATERESEARCHOPTIONTHESIS-2016.pdf (634.9Kb)
    Date
    2016-07-18
    Author
    Shin, Chong In
    Metadata
    Show full item record
    Abstract
    The cause of Alzheimer’s disease are the deposits of Amyloid-Beta (Aβ) protein fragments and the twisted fibers of tau proteins. These proteins build up inside the brain inducing the destruction and death of nerve cells which eventually results in symptoms such as memory failure, personality changes and more. To find a treatment for this disease, many studies have relied on using potential modulators to prevent the formation of the plaques and find potential cures. no molecular dynamics simulation has been done on norepinephrine to investigate the interaction with Aβ proteins. Hence, the purpose of this study is to observe and determine the exact mechanism involved in the interaction between 3,4-dihydroxymandelic acid (DHMA), normetanephrine (NMN), which are metabolites of norepinephrine, and amyloid-beta protein through molecular dynamics simulations.
    URI
    http://hdl.handle.net/1853/55386
    Collections
    • Undergraduate Research Option Theses [631]
    • Department of Biomedical Engineering Undergraduate Research Option Theses [169]

    Browse

    All of SMARTechCommunities & CollectionsDatesAuthorsTitlesSubjectsTypesThis CollectionDatesAuthorsTitlesSubjectsTypes

    My SMARTech

    Login

    Statistics

    View Usage StatisticsView Google Analytics Statistics
    • About
    • Terms of Use
    • Contact Us
    • Emergency Information
    • Legal & Privacy Information
    • Accessibility
    • Accountability
    • Accreditation
    • Employment
    • Login
    Georgia Tech

    © Georgia Institute of Technology

    • About
    • Terms of Use
    • Contact Us
    • Emergency Information
    • Legal & Privacy Information
    • Accessibility
    • Accountability
    • Accreditation
    • Employment
    • Login
    Georgia Tech

    © Georgia Institute of Technology