Browsing GT Neuro Seminar Series by Title
Now showing items 8-27 of 77
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Cholinergic Sensorimotor Integration Regulates Rapid Behavioral Decisions
(2018-04-16)During active exploration, the spatial and temporal pattern of the sensory cue perceived by an animal is shaped by the animal’s own movement. Thus, to move towards a sensory target, the nervous system needs to make rapid ... -
Cortical Circuits of Vision
(2017-04-24)The diversity of neuron types and synaptic connectivity patterns in the mammalian cerebral cortex is astonishing. How this cellular and synaptic diversity contributes to cortical function is just beginning to emerge. Using ... -
Corticocortical Communication
(2020-02-10)Most brain functions involve neuronal population activity that is distributed across multiple areas. The routing of signals through this distributed network is flexible, changing from moment-to-moment to meet task demands. ... -
Deconstructing Memory Circuits at Cell Type-specific Resolution
(2019-01-28)Nelson Spruston studies the hippocampus, with an emphasis on uncovering the diversity and complexity of cells and synapses that allow this brain structure to contribute to memory-guided behavior, such as spatial navigation ... -
Defining neuromodulation targets for PTSD using neuroimaging
(2021-02-01)Posttraumatic stress disorder (PTSD) is a serious psychiatric condition that affects 6-8% of the general population and 30-46% of military or highly traumatized urban populations. Different neuromodulation techniques are ... -
Dissection of Neural Circuit Function and Degeneration from a Subcellular Perspective
(2020-02-17)How do neurons perform the set of signaling functions necessary for proper circuit function? We aim to uncover cellular and molecular mechanisms that shape excitability among different mammalian neurons. We approach these ... -
Distinct Neuronal Ensembles Encode Sensory Stimulus Context in the Neocortex
(2018-11-19)The Hamm lab conducts basic research on cortical microcircuitry with paradigms and approaches designed to provide deeper insight into neuropsychiatric disease. Sensory processing abnormalities in schizophrenia (SZ) undermine ... -
The Dynamics of Perceptual Decision Making
(2017-02-13)How do humans and other animals make decisions? A large body of work has investigated this question in the perceptual domain where subjects make decisions about simple visual stimuli. A critical question concerns the ... -
Ecological resources and the evolution of parent-offspring interactions
(2020-11-23)Animal behavior is a key component of biological adaptations, where fitness relies on the ability to find mates, acquire food, and avoid predation. Variation in the availability of key ecological resources can drive the ... -
Effects of Nicotine on Brain and Behavior: How nAChRs Modulate Circuits Related to Mood and Aggression
(2018-03-12)Acetylcholine signaling influences behaviors related to diverse functions, including drug abuse, attention, food intake, and mood. The ability of acetylcholine to coordinate the response of neuronal networks in many brain ... -
Engineering Neurotechnology for the Surgical Treatment of Epilepsy: A Surgeon-scientist-non-engineer’s Perspective
(2018-10-29)(1) Cellular and Gene Therapy for Parkinson’s Disease Elucidation of the role of axon guidance molecules in the development and reconstruction of the nigrostriatal pathway, which degenerates in Parkinson’s Disease, and ... -
Epilepsy – Beyond the Local Network
(2019-10-28)While human research has emphasized the large-scale network disruptions in the epilepsies and their co-morbidities, basic science has typically focused on local networks. In rodents, more general large-scale network dynamics ... -
Evolution and Development of a Minimal Nervous System in our Closest Invertebrate Relatives
(2019-11-25)Animal behavior depends both on the intrinsic properties of individual neurons and how these neurons connect to and modulate one another. A major focus of modern neuroscience is to dissect behavior at the level of individual ... -
Evolutionarily Conserved Mechanisms of Sociality
(2019-10-07)There is an extraordinary amount of variation in social behavior within and across species. However, when phenotypic convergence in behavior (e.g., sociality) is observed, it begs the question as to whether the same neural ... -
Finding Low-dimensional Structure in Large-scale Neural Recordings
(2018-02-12)Improvements in neural recording technologies have rapidly increased the number of neurons that it is now possible to record from. Along with these improvements, analyses of neural information processing are moving from ... -
Flexible Learning and Decision Making in a Changing World
(2020-10-19)Survival requires proper association of reward outcomes to choices and actions that precede them. To learn successfully, however, the brain must constantly adjust how it incorporates each reward feedback because the ... -
A Functional Cortical Network for Sensorimotor Sequence Generation
(2020-01-27)Daniel O'Connor discusses his laboratory’s recent work on the sensorimotor control of complex tongue movements. The brain generates complex sequences of movements that can be flexibly reconfigured in real-time based on ... -
Functional Imaging of the Human Brain: A Window into the Architecture of the Mind
(2019-09-16)The last 20 years of brain imaging research has revealed the functional organization of the human brain in glorious detail, including dozens of cortical regions each of which is specifically engaged in a particular mental ... -
Genetic Dissection of Spinal Circuits Processing Mechanical Itch
(2018-04-02)We have all experienced an itch. It is a modality of somatic sensation defined as an unpleasant sensation associated with the desire to scratch. Itch can be evoked in the skin directly by physical stimuli, such as gentle ... -
Hippocampal Codes in Spatial Memory and Alzheimer’s Disease
(2016-10-31)The hippocampus is essential for both spatial navigation and episodic memory. While decades of research has revealed patterns of neural activity in the hippocampus that represent information about the spatial environment, ...
