Browsing GT Neuro Seminar Series by Title
Now showing items 22-41 of 77
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Finding Low-dimensional Structure in Large-scale Neural Recordings
(2018-02-12)Improvements in neural recording technologies have rapidly increased the number of neurons that it is now possible to record from. Along with these improvements, analyses of neural information processing are moving from ... -
Flexible Learning and Decision Making in a Changing World
(2020-10-19)Survival requires proper association of reward outcomes to choices and actions that precede them. To learn successfully, however, the brain must constantly adjust how it incorporates each reward feedback because the ... -
A Functional Cortical Network for Sensorimotor Sequence Generation
(2020-01-27)Daniel O'Connor discusses his laboratory’s recent work on the sensorimotor control of complex tongue movements. The brain generates complex sequences of movements that can be flexibly reconfigured in real-time based on ... -
Functional Imaging of the Human Brain: A Window into the Architecture of the Mind
(2019-09-16)The last 20 years of brain imaging research has revealed the functional organization of the human brain in glorious detail, including dozens of cortical regions each of which is specifically engaged in a particular mental ... -
Genetic Dissection of Spinal Circuits Processing Mechanical Itch
(2018-04-02)We have all experienced an itch. It is a modality of somatic sensation defined as an unpleasant sensation associated with the desire to scratch. Itch can be evoked in the skin directly by physical stimuli, such as gentle ... -
Hippocampal Codes in Spatial Memory and Alzheimer’s Disease
(2016-10-31)The hippocampus is essential for both spatial navigation and episodic memory. While decades of research has revealed patterns of neural activity in the hippocampus that represent information about the spatial environment, ... -
How a Fly Sees the World: Optogenetics, Systems ID, and Optophysiology of Visual Flight Control in Drosophila
(2017-11-06)Flies have remarkably high performance visual systems that operate at the physical and physiological limits of seeing their world as they fly through it. Flies use the pattern of panoramic optic flow to stabilize their ... -
How hippocampal memory shapes, and is shaped by, attention
(2020-09-14)Attention modulates what we see and remember. Memory affects what we attend to and perceive. Despite this connection in behavior, little is known about the mechanisms that link attention and memory in the brain. One key ... -
How the Cortex Regulates the Thalamus
(2016-10-17)The thalamus provides sensory information to the cerebral cortex, but the cortex also sends massive input to the thalamus. Top-down corticothalamic projections may allow the cortex to regulate sensory processing by modulating ... -
How to Improve Detection and Treatment of Diabetic Retinopathy
(2017-03-27)Diabetic retinopathy (DR) is the leading cause of blindness in working age adults. DR is clinically diagnosed by late stage vascular changes in the retina. Detecting early stage retinopathy prior to the onset of these ... -
Identifying and Targeting Potential Biomarkers of Motor Dysfunction after Stroke using Non-invasive Neurostimulation and Neuroimaging
(2016-09-19)Up to 80% of stroke survivors have persistent motor impairment of the paretic arm that interferes with performing functional activities and limits activity participation. Stroke can trigger maladaptive changes in the ... -
Imaging the brain at high spatiotemporal resolution
(2019-04-01)Physics has long employed optical methods to probe and manipulate matter on scales from the infinitesimal to the immense. To understand the brain, we need to monitor physiological processes of single synapses as well as ... -
Impact of Seizures in Memory Performance on a NHP Model of Temporal Lobe Epilepsy
(2018-10-22)There is a lot of controversial finding on how epileptic activities (seizures and interictal epileptiform discharge) affect cognition in both animals and humans. Mesial temporal lobe epilepsy (MTLE) is one of the most ... -
Inhibitory Control of Cortical Activity in vivo
(2016-10-24)The cerebral cortex is the largest and most complicated structure of the mammalian brain. The cortex generates many regimes of spontaneous and sensory evoked activity. What are the cellular and circuit mechanisms that ... -
Integrating New Knowledge into a Neural Network without Catastrophic Interference: Computational and Theoretical Investigations in a Hierarchically Structured Environment
(2019-04-15)According to complementary learning systems theory, integrating new memories into a multi-layer neural network without interfering with what is already known depends on interleaving presentation of the new memories with ... -
Itch Receptors in the Airway
(2016-09-29)We use a combination of molecular, cellular, immunohistochemical, electrophysiological, genetic and behavioral approaches to understand how the nervous system receive, transmit and interpret various stimuli to induce ... -
Iterative Strategies to Refine and Optimize Deep Brain Stimulation for Depression
(2017-10-23)It is now more than twelve years since the first study of Deep Brain Stimulation (DBS) for treatment resistant depression (TRD). While multiple centers, testing this and other targets, have replicated these initial positive ... -
Light: A Powerful Tool for Brain Monitoring
(2017-09-18)This talk will provide an overview of diffuse optical spectroscopies used to non-invasively measure cerebral blood flow, oxygen metabolism, oxygen saturation, and blood volume. Further it will highlight how quantification ... -
Map Making in C. elegans: Charting the Nervous System
(2016-12-12)The developmental history and anatomy of the nematode C.elegans has been exceptionally well mapped. The next frontier lies in taking maps to the next level, that of molecular maps which define the identity and function of ...
