Now showing items 1-19 of 19

    • The Modular Brain 

      D'Esposito, Mark (Georgia Institute of Technology, 2016-09-09)
      What type of system is the brain? The brain is widely assumed to be one of many modular systems in nature, which are thought to be computational tractable and favored by evolution. While focal brain lesions lead to very ...
    • Vocal Motor Control and Sensorimotor Learning: Behavior, Physiology, and Biomechanics 

      Sober, Samuel (Georgia Institute of Technology, 2016-09-12)
      The brain uses sensory feedback to calibrate the performance of complex behaviors. However, the neural and computational bases of sensorimotor learning remain mysterious. Our lab uses behavioral, physiological, biomechanical, ...
    • Identifying and Targeting Potential Biomarkers of Motor Dysfunction after Stroke using Non-invasive Neurostimulation and Neuroimaging 

      Borich, Michael (2016-09-19)
      Up to 80% of stroke survivors have persistent motor impairment of the paretic arm that interferes with performing functional activities and limits activity participation. Stroke can trigger maladaptive changes in the ...
    • Itch Receptors in the Airway 

      Han, Liang (2016-09-29)
      We use a combination of molecular, cellular, immunohistochemical, electrophysiological, genetic and behavioral approaches to understand how the nervous system receive, transmit and interpret various stimuli to induce ...
    • How the Cortex Regulates the Thalamus 

      Connors, Barry (2016-10-17)
      The thalamus provides sensory information to the cerebral cortex, but the cortex also sends massive input to the thalamus. Top-down corticothalamic projections may allow the cortex to regulate sensory processing by modulating ...
    • Inhibitory Control of Cortical Activity in vivo 

      Haider, Bilal (2016-10-24)
      The cerebral cortex is the largest and most complicated structure of the mammalian brain. The cortex generates many regimes of spontaneous and sensory evoked activity. What are the cellular and circuit mechanisms that ...
    • Hippocampal Codes in Spatial Memory and Alzheimer’s Disease 

      Singer, Annabelle (2016-10-31)
      The hippocampus is essential for both spatial navigation and episodic memory. While decades of research has revealed patterns of neural activity in the hippocampus that represent information about the spatial environment, ...
    • Biophysically Principled Modeling of Human MEG/EEG Signals Reveals Novel Mechanisms and Meaning of Brain Rhythms 

      Jones, Stephanie (2016-11-28)
      Magneto- and Electro-encephalography (MEG/EEG) are among the most powerful technologies to non-invasively record large-scale activity from humans with fine temporal and spatial resolution. These signals provide reliable ...
    • Mapping the Structure of Animal Behavior 

      Berman, Gordon (2016-12-05)
      Animals perform a complex array of behaviors, from changes in body posture to vocalizations to other dynamic outputs. Far from being a disordered collection of actions, however, there is thought to be an intrinsic structure ...
    • Map Making in C. elegans: Charting the Nervous System 

      Hobert, Oliver (2016-12-12)
      The developmental history and anatomy of the nematode C.elegans has been exceptionally well mapped. The next frontier lies in taking maps to the next level, that of molecular maps which define the identity and function of ...
    • Principles of Motor Control 

      Chiel, Hillel J. (2017-01-23)
      How does the nervous system control behavior? To answer this question requires an understanding of neural circuitry, biomechanics, and behavior. To address this question, we have studied an experimentally tractable ...
    • Neural Dynamics of the Primate Attention Network 

      Kastner, Sabine (2017-01-30)
      The selection of information from our cluttered sensory environments is one of the most fundamental cognitive operations performed by the primate brain. In the visual domain, the selection process is thought to be mediated ...
    • Bringing Bioelectricity to Light 

      Cohen, Adam (2017-02-06)
      To study a neural circuit, one would like to probe the activity of many neurons, with high resolution in space and time. A key challenge has been the difficulty of visualizing changes in transmembrane potential. We discovered ...
    • The Dynamics of Perceptual Decision Making 

      Rahnev, Dobromir (2017-02-13)
      How do humans and other animals make decisions? A large body of work has investigated this question in the perceptual domain where subjects make decisions about simple visual stimuli. A critical question concerns the ...
    • What Can Neuroimaging Tell Us About Age-related Memory Changes? 

      Duarte, Audrey (2017-02-27)
      One of the most common and arguably most distressing such declines in aging, in large part because it is also an early sign of Alzheimer’s disease, is that of associative memory. Associative memory is the ability to bind ...
    • Rethinking Recovery and Rehabilitation after Stroke 

      Krakauer, John (2017-03-06)
      There are critical differences in the potential for rehabilitation of impairment early and late after stroke. Early after stroke the proportional recovery rule for spontaneous biological recovery applies, as does the idea ...
    • How to Improve Detection and Treatment of Diabetic Retinopathy 

      Pardue, Machelle (2017-03-27)
      Diabetic retinopathy (DR) is the leading cause of blindness in working age adults. DR is clinically diagnosed by late stage vascular changes in the retina. Detecting early stage retinopathy prior to the onset of these ...
    • Using the Past to Predict the Future: Applications of High Throughput Longitudinal Single Cell Analysis, Genomics, Stem Cells and Machine Learning to Discovery 

      Finkbeiner, Steve (2017-04-10)
      Clinical trial failure rates for neurological diseases are some of the highest of any indication (~93%), despite showing promise in preclinical disease models. The poor predictive power of preclinical models is a major ...
    • Cortical Circuits of Vision 

      Scanziani, Massimo (2017-04-24)
      The diversity of neuron types and synaptic connectivity patterns in the mammalian cerebral cortex is astonishing. How this cellular and synaptic diversity contributes to cortical function is just beginning to emerge. Using ...