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dc.contributor.authorHaider, Bilal
dc.date.accessioned2016-11-08T15:41:25Z
dc.date.available2016-11-08T15:41:25Z
dc.date.issued2016-10-24
dc.identifier.urihttp://hdl.handle.net/1853/56011
dc.descriptionPresented on October 24, 2016 at 11:00 a.m. in the Engineered Biosystems Building, Room 1005.en_US
dc.descriptionBilal Haider is an assistant professor of biomedical engineering at Georgia Institute of Technology & Emory University in Atlanta. His research focuses on synaptic and network mechanisms that allow neurons in the cerebral cortex to modulate their response properties during sensory perception and behavior.en_US
dc.descriptionRuntime: 54:59 minutesen_US
dc.description.abstractThe cerebral cortex is the largest and most complicated structure of the mammalian brain. The cortex generates many regimes of spontaneous and sensory evoked activity. What are the cellular and circuit mechanisms that determine these regimes? What consequences do they have for sensory processing? And how do these mechanisms vary across behavioral states? To address these questions, I will present three electrophysiological studies of spiking and sub-threshold (synaptic) activity recorded from specific cortical neuron types in vivo. First, I will show that cortical excitation and inhibition closely balance each other during ongoing spontaneous activity. I will next show how inhibitory circuits are recruited to produce reliable and precise cortical activity during naturalistic visual stimulation. Finally, I will show that in the awake cortex, the specific activation of inhibitory circuits dramatically sharpens the spatial and temporal resolution of visual processing. This enhanced role of inhibition during wakefulness shapes how excitatory neuron populations relate to sensory events. Taken together, these studies suggest that cortical inhibitory circuits play the dominant role in rapid modulation of sensory processing according to the demands of the environment and behavior.en_US
dc.format.extent54:59 minutes
dc.relation.ispartofseriesGT Neuro Seminar Seriesen_US
dc.subjectCerebral cortexen_US
dc.subjectNeuroscienceen_US
dc.titleInhibitory Control of Cortical Activity in vivoen_US
dc.typeLectureen_US
dc.typeVideoen_US
dc.contributor.corporatenameGeorgia Institute of Technology. Neural Engineering Centeren_US
dc.contributor.corporatenameGeorgia Institute of Technology. Wallace H. Coulter Dept. of Biomedical Engineeringen_US


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