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    Variants Of Ancestral Uricases And Uses Thereof

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    8940861.pdf (1.204Mb)
    Date
    1/27/2015
    Author
    Gaucher, Eric A.
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    Abstract
    The present invention provides uricases and methods of their production and use in reducing the amount of uric acid in a subject. The present invention further provides methods employing a uricase of this invention in the treatment and/or prevention of hyperuricemia, gout, tumor lysis syndrome and/or hypertension in a subject.
    URI
    http://hdl.handle.net/1853/56954
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