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    Histone Deacetylase (HDAC) Inhibitors Targeting Prostate Tumors And Methods Of Making And Using Thereof

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    Date
    9/22/2015
    Author
    Oyelere, Adegboyega
    Gryder, Berkley
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    Abstract
    Compounds of Formula (I), and methods of making and using thereof, are described herein; wherein AR is an aryl group, ZBG is a Zinc Binding Group, and other substituents are as defined herein. The compounds can be administered as a pharmaceutically acceptable salt, prodrug, or solvate. The compounds may be useful to treat and/or prevent hyperproliferative disorders which may include hormone sensitive and hormone refractory prostate cancers. The compounds can be formulated with a pharmaceutically acceptable carrier and, optionally one or more pharmaceutically acceptable excipients, for enteral or parenteral administration.
    URI
    http://hdl.handle.net/1853/57021
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    • Georgia Tech Patents [1761]

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