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    PNA Monomers With Electron Donor Or Acceptor

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    6117973.pdf (1.591Mb)
    Date
    9/12/2000
    Author
    Batz, Hans-georg
    Hansen, Henrik Frydenlund
    Orum, Henrik
    Koch, Troels
    Shuster, Gary B.
    Armitage, Bruce A.
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    Abstract
    New electron transfer moiety labeled nucleic acid analogue probes are provided that can be used in methods for determining nucleic acids in a sample. The new probes can be prepared using novel monomer subunits in a chemical synthesis route. The nucleic acids can be determined by binding the probe molecules to the nucleic acid and inducing electron transfer within the complex formed. The occurrence of the electron transfer is determined as a measure of the nucleic acid.
    URI
    http://hdl.handle.net/1853/57351
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