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    Propenoyl Hydrazides

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    7482379.pdf (2.566Mb)
    Date
    1/27/2009
    Author
    Powers, James C.
    Asgian, Juliana
    Ekici, Özlem Dogan
    Gotz, Marion Gabriele
    James, Karen Ellis
    Li, Zhao Zhao
    Rukamp, Brian
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    Abstract
    The present disclosure provides compositions for inhibiting proteases, methods for synthesizing the compositions, and methods of using the disclosed protease inhibitors. Aspects of the disclosure include a peptidyl propenoyl hydrazide compositions that inhibit proteases, for example cysteine proteases, either in vivo or in vitro.
    URI
    http://hdl.handle.net/1853/57780
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