Identification of leukemia and cancerous leukocytes based on biophysical properties

Abstract

The goal of the research described in this thesis is to determine size, elasticity, and viscoelasticity of 4 leukocyte cell types, neutrophils, lymphocytes, HL60, and Jurkat. HL60 is a representative of Acute Myeloid Leukemia (AML), and Jurkat is representative of Acute T cell leukemia (ALL). Neutrophils and Lymphocytes are two different types of healthy white blood cells. We believe it is possible to differentiate cells only using mechanical characteristics.