Microfluidic Circuits and Biomedical Applications
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This presentation will give an overview of efforts in our laboratory to develop microfluidic systems to control cell microenvironments and to perform high precision biochemical measurements. Microfluidic technologies to be discussed include computer-controlled microfluidics, self-switching microfluidic transistor-like circuitry, microfluidics that utilize aqueous two phase droplets, and fracture fabrication of tunable nanochannels. Specific biomedical applications that will be discussed include lung-on-a-chip, microfluidic assisted reproductive technologies and in vitro fertilization, heartbeat-on-a-chip, chromatin analysis in fracture-fabricated nanochannels, and protein biomarker analysis. The long-term goal is to create miniature patients-on-a-chip for understanding disease mechanisms, testing drugs, performing better cell-based therapies, and validating protein biomarkers.
- Nano@Tech Lecture Series