The Wallace H. Coulter Department of Biomedical Engineering (BME)
The role of the biomedical engineer is to provide answers to problems arising from the study of living systems by employing the methodology and principles of engineering. We are now embarking on the Biomedical Century, and the need for engineers trained in biomedicine is increasing at a tremendous pace.
In September 1997, after an intense planning and review process that involved faculty from both institutions, Georgia Tech joined with Emory University School of Medicine to establish The Wallace H. Coulter Department of Biomedical Engineering (BME).
All materials in SMARTech are protected under U.S. Copyright Law and all rights are reserved. Such materials may be used, quoted or reproduced for educational purposes only with prior permission, provided proper attribution is given. Any redistribution, reproduction or use of the materials, in whole or in part, is prohibited without prior permission of the author.
Sub-communities within this community
-
Department of Biomedical Engineering Seminars, Symposia, and Workshops [9]
Seminars, Symposia, and Workshops hosted by the The Wallace H. Coulter Department of Biomedical Engineering
Collections in this community
-
Biomedical Engineering Technical Reports [32]
Papers and articles produced by Dr. Brani Vidakovic's research -
Biomedical Imaging Lab (Minerva Research Group) [210]
Research produced by the Minerva Research Group in the Biomedical Imaging Lab -
Department of Biomedical Engineering Faculty Publications [66]
Papers, Pre/Post-Prints, and Presentations by Faculty in the Department of Biomedical Engineering -
Department of Biomedical Engineering OSP Research Reports [20]
Office of Sponsored Programs research reports by faculty and researchers in the Department of Biomedical Engineering -
Department of Biomedical Engineering Theses and Dissertations [522]
Original work by students in the Department of Biomedical Engineering -
Department of Biomedical Engineering Undergraduate Research Option Theses [188]
Research Thesis Option for Biomedical Engineering Majors
Recent Submissions
-
An Evaluation of Polymeric Nanoparticles as an Alternative for Vaccinations
Although many studies have been done on antibodies and vaccines, little is known about the transfection methods of nanoparticles capable of carrying antigens into cells to create effective mRNA vaccines. Although mRNA ... -
Fracture Mechanics of Pelleted Feces Within Mammals
In this combined experimental and theoretical study, we test the hypothesis that feces length is set by the dynamics of drying within the intestine. With previous measurements of the water contents of both pelleted and ... -
Sleep Disruption in a Mouse Model of Medial Temporal Lobe Epilepsy
While not typically a recognized comorbidity of epilepsy, sleep disorders are common in epilepsy, particularly medial temporal lobe epilepsy (MTLE). However, consistent and severe sleep disruptions have a potentially ... -
Glial Fibrillary Acidic Protein (GFAP) Response in a Preclinical Rat Model of mTBI Glial Fibrillary Acidic Protein (GFAP) Response in a Preclinical Rat Model of mTBI
Traumatic brain injury (TBI) impairs populations both physically and financially, explaining about 75% of all head injuries and costing over $60 billion in the United States (Ahmed et.al, 2015 and Maas et. al, 2010). Through ... -
The Selective Benefits of Acute Dosing with Dopamine Receptor Agonists on the Visual Function, Cognitive Function, and Blood Glucose Levels in a Rat Model of Type I Diabetes
Purpose: Previous studies have demonstrated that dopamine D1 and D4 receptor (D1R, D4R) agonists selectively improve spatial frequency and contrast sensitivity thresholds, respectively, in healthy and diabetic mice (Jackson ... -
3D bioprinted cardiac patches for cardiovascular regenerative medicine
Myocardial infarction (MI) is the leading cause of death worldwide causing irreversible damage to the heart. Despite the incidence and prevalence of MI, current treatments delay the progression of the damage rather than ... -
A System to Measure Maximal Isometric Torque of the Mouse Quadriceps to Assess Functional Recovery of Skeletal Muscle in a Volumetric Muscle Loss Injury
Volumetric muscle loss (VML) is an injury characterized by the traumatic or surgical loss of skeletal muscle and a severe loss of function to the affected limb. Due to the injury’s size and complexity, the body is unable ... -
Improving Mitral Repair for Functional Mitral Regurgitation
Ischemic mitral regurgitation is affiliated with changes in annular dimensions as well as remodeling of the left ventricle. Undersized mitral annuloplasty (UMA), which involves implanting a titanium-based ring-like structure ... -
Characterizing Excitatory and Inhibitory Neuron Responses to Dark and Bright Stimuli in the Visual Cortex of Awake Mice
An increased understanding in mouse primary visual cortex (V1) will allow us to better characterize the internal electrical and neural circuit mechanisms of the visual process. So far, most studies directly recording single ... -
Characterizing the Dynamics of Macrophage Polarization and Signaling
Apart from their primary functions in innate immunity and phagocytosis, macrophages are critical regulators of inflammation through their ability to adopt polarization states, a spectrum of phenotypes in which macrophages ... -
Engineering genetic thermal switches for remote control of therapeutic T cells
Adoptive transfer of engineered T cells has shown striking clinical success in treating refractory liquid cancers, yet the inability to spatially regulate T cell activity within select anatomical sites limits efficacy ... -
Anti-CRISPRs Oligonucleotides Facilitate Cell Type-Specific Control of Nanoparticle Cas9 Gene Editing
While CRISPR-Cas systems represent a powerful research tool, in order to become clinically viable significant challenges woud have to be overcome. One of the largest issues facing the breadth of CRISPR technologies is the ... -
Effect of transcatheter aortic valve materials on thrombogenesis
Transcatheter aortic valve replacement (TAVR) is a minimally invasive technique introduced to treat patients with aortic stenosis who are at high surgical risk. Despite its advantages over the traditional open-heart surgery ... -
Hyaluronan Physically Mediates Cell Adhesion
Cell adhesion is the fundamental process underlying all basic life processes. While structures that enhance cell adhesion strength, such as focal adhesions, have been widely characterized, influences decreasing cell adhesion ... -
Modulation of DNA Methylation for Efficient Differentiation of Neural Stem Cells
Epigenetic mechanisms are pivotal for gene regulation and transcription, which are crucial to a proper functioning of the central nervous system (CNS). Numerous neurological and psychiatric diseases are caused by malfunctions ... -
Convective intracellular macromolecule delivery for cell engineering applications
(Georgia Institute of Technology, 2020-04-25)Efficient intracellular delivery of target macromolecules remains a major obstacle in cell engineering, cell labeling, and other biomedical applications. Current standard methods of intracellular delivery, such as viral ... -
Perfluorocarbon Nanodroplets for Extravascular Imaging Applications
(Georgia Institute of Technology, 2020-04-23)Gas microbubbles are the contrast agent of choice for ultrasound imaging. These agents are excellent for highlighting vasculature; however, their micrometer-scale size prevents them from efficient trafficking within ... -
Engineering Nucleic Acid Nanostructures for Sensing and Control of Biomolecules and Their Environments
(Georgia Institute of Technology, 2020-05-05)Nucleic acid nanotechnology has emerged in the past decade as a powerful and versatile method to create functional and programmable nanostructures through molecular self-assembly. The research presented in this dissertation ... -
Development of Methodology to Estimate Fractional Flow Reserve Using Magnetic Resonance Imaging and Computational Fluid Dynamics
(Georgia Institute of Technology, 2020-04-09)Fractional flow reserve is the current gold standard for evaluating severity of coronary artery disease, but it is underutilized clinically due to its invasiveness. Recent efforts have worked toward developing non-invasive ... -
DNA Nanotechnology to Map and Manipulate Adhesion Forces at Fluid Interfaces
(Georgia Institute of Technology, 2020-03-27)Cells transmit piconewton (pN) receptor forces to ligands in the extracellular matrix (ECM) and on the surface of adjacent cells. These forces regulate functions ranging from adhesion to clotting and the immune response. ...
RSS 1.0