The Wallace H. Coulter Department of Biomedical Engineering (BME)
The role of the biomedical engineer is to provide answers to problems arising from the study of living systems by employing the methodology and principles of engineering. We are now embarking on the Biomedical Century, and the need for engineers trained in biomedicine is increasing at a tremendous pace.
In September 1997, after an intense planning and review process that involved faculty from both institutions, Georgia Tech joined with Emory University School of Medicine to establish The Wallace H. Coulter Department of Biomedical Engineering (BME).
All materials in SMARTech are protected under U.S. Copyright Law and all rights are reserved. Such materials may be used, quoted or reproduced for educational purposes only with prior permission, provided proper attribution is given. Any redistribution, reproduction or use of the materials, in whole or in part, is prohibited without prior permission of the author.
Sub-communities within this community
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Department of Biomedical Engineering Seminars, Symposia, and Workshops [9]
Seminars, Symposia, and Workshops hosted by the The Wallace H. Coulter Department of Biomedical Engineering
Collections in this community
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Biomedical Engineering Technical Reports [32]
Papers and articles produced by Dr. Brani Vidakovic's research -
Biomedical Imaging Lab (Minerva Research Group) [210]
Research produced by the Minerva Research Group in the Biomedical Imaging Lab -
Department of Biomedical Engineering Faculty Publications [66]
Papers, Pre/Post-Prints, and Presentations by Faculty in the Department of Biomedical Engineering -
Department of Biomedical Engineering OSP Research Reports [16]
Office of Sponsored Programs research reports by faculty and researchers in the Department of Biomedical Engineering -
Department of Biomedical Engineering Theses and Dissertations [382]
Original work by students in the Department of Biomedical Engineering -
Department of Biomedical Engineering Undergraduate Research Option Theses [64]
Research Thesis Option for Biomedical Engineering Majors
Recent Submissions
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Investigating scaffold designs for progenitor cells-based cell therapy for cardiac repair
(Georgia Institute of Technology, 2017-04-06)Cell therapy for congestive heart failure has shown promising results in preclinical studies, but results of clinical trials suggest the need for this modality to be optimized. C-kit+ cardiac progenitor cells (CPCs) are ... -
Optical Sectioning Microscopy with Spatial Modulated Excitation Laser
(Georgia Institute of Technology, 2017-04-03)Optical microscopy is one of the most widely used tools in biomedical researches. However, in the observation of thick biological samples, conventional optical microscopes suffer from background from out-of-focus structures. ... -
High-Throughput Screening Identifies Micrornas that Target NOX2 and Improve Function Following Acute Myocardial Infarction
(Georgia Institute of Technology, 2017-04-06)MicroRNAs (miRNAs) are small non-coding RNAs that can regulate gene expression by inducing either degradation or translational inhibition of a target mRNA. miRNAs have been indicated to regulate up to 90% of human genes ... -
Human peripheral reticulocyte isolation and exosome release in vitro
(Georgia Institute of Technology, 2017-04-03)The exosomes released by peripheral reticulocytes were originally thought to function as vehicles for protein clearance for the maturing cells. With the emergence of exosomes as mediators of intercellular communication, ... -
MECHANISMS DURING CATHEPSIN INHIBITION AND THE EFFECTS ON SUBSTRATE DEGRADATION AND BREAST CANCER CELL INVASION
(Georgia Institute of Technology, 2016-04-12)Mechanisms during cathepsin inhibition and the effects on substrate degradation and breast cancer cell invasion Catera L. Wilder 123 Pages Directed by Dr. Manu O. Platt Cysteine cathepsin proteases are powerful collagenases ... -
Defining the Neuromuscular Mechanisms of Vocal Motor Control
(Georgia Institute of Technology, 2016-03-30)The manner in which the brain sends commands to muscles to enact behavior is instrumental to our ability to interact with our environment. Moreover, the control of complex vocalizations is crucial for communicating with ... -
Strategies for Controlling the Innate Immune Responses to in vitro Transcribed Messenger RNAs
(Georgia Institute of Technology, 2016-03-15)Synthetic messenger RNA (mRNA) produced via in vitro transcription (IVT mRNA) has emerged as an appealing tool for the transient introduction of genes, particularly for vaccination applications. The interaction that IVT ... -
The Role and Regulation of Osteopontin in Hypertension Related Remodeling and Inflammation of the Aorta
(Georgia Institute of Technology, 2016-01-15)The arterial wall experiences elevated mechanical strain in the setting of hypertension, which leads to vascular inflammation and atherosclerosis. However, many of the underlying molecular mechanisms modulating this ... -
Variability and control of activity in small neural networks: effects of neuron feedback dynamics
(Georgia Institute of Technology, 2016-01-15)Rhythmic neural networks are dynamic systems that reliably generate stereotyped activity that drives numerous biological processes essential to life, including motor pattern generation. Due to these networks’ reliable ... -
Development and application of inhibitory luminopsins for the treatment of epilepsy
(Georgia Institute of Technology, 2016-01-15)Optogenetics has shown great promise as a direct neuromodulatory tool for halting seizure activity in various animal models of epilepsy. However, light delivery into the brain is still a major practical challenge that needs ... -
High-Throughput Screening Identifies Micrornas That Target Nox2 and Improve Function Following Acute Myocardial Infarction
(Georgia Institute of Technology, 2017-02-24)Myocardial infarction (MI) is the most common cause of heart failure. Excessive production of reactive oxygen species plays a key role in the pathogenesis of cardiac remodeling after MI. NADPH with Nox2 as the catalytic ... -
Optimization of Robot Configurations for Assistive Tasks
(Georgia Institute of Technology, 2016)Robots can provide assistance with activities of daily living (ADLs) to humans with motor impairments. Specialized robots, such as desktop robotic feeding systems, have been successful for specific assistive tasks when ... -
Autobed: Open Hardware for Accessible Web-based Control of an Electric Bed
(Georgia Institute of Technology, 2016)Individuals with severe motor impairments often have difficulty operating the standard controls of electric beds and so require a caregiver to adjust their position for utility, comfort, or to prevent pressure ulcers. ... -
Material Recognition from Heat Transfer given Varying Initial Conditions and Short-Duration Contact
(Georgia Institute of Technology, 2015)When making contact with an object, a robot can use a tactile sensor consisting of a heating element and a temperature sensor to recognize the object’s material based on conductive heat transfer from the tactile sensor ... -
Computational modeling of mechanical heart valves
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The influence of sex-dependent vascular properties on aortic hemodynamics
(Georgia Institute of Technology, 2016-11-16)The motivation of this work stems from the lack of information regarding how differences in cardiovascular biomechanics between men and women underlie differences in abdominal aortic aneurysm disease. More specifically, ... -
Influence of static and dynamic topography on osteoblast proliferation and maturation
(Georgia Institute of Technology, 2016-11-15)Osseointegration remains a primary concern for implanted devices in patients with risk factors such as diabetes, smoking, age, arthritis, and osteoporosis. Current use of titanium alloys, while successful, comes at a high ... -
Multi-scale structural design of titanium implants for improved osseointegration
(Georgia Institute of Technology, 2016-11-07)Osseointegration success of bone-interfacing implants is reduced for many compromised patients, necessitating improved implant design. Though material and mechanical properties of titanium make it attractive for load-bearing ... -
Heparin and PEG-Based Hydrogels to Modulate and Interrogate Dynamic Cell Behavior
(Georgia Institute of Technology, 2016-10-14)Hydrogel-based biomaterials are often used for biomolecule delivery or encapsulation of cells for tissue engineering and regenerative medicine applications. However, utilizing hydrogels in dynamic cell systems can be ... -
OPTIMIZING SENSORY STIMULATION IN HUMANS AFTER SPINAL CORD INJURY
(Georgia Institute of Technology, 2016-08-31)Sensory stimulation has shown promise in improving human walking after spinal cord injury (SCI). Previous studies have demonstrated some improvement with open-loop, non-individualized sensory stimulation, but after SCI, ...
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