The Wallace H. Coulter Department of Biomedical Engineering (BME)
The role of the biomedical engineer is to provide answers to problems arising from the study of living systems by employing the methodology and principles of engineering. We are now embarking on the Biomedical Century, and the need for engineers trained in biomedicine is increasing at a tremendous pace.
In September 1997, after an intense planning and review process that involved faculty from both institutions, Georgia Tech joined with Emory University School of Medicine to establish The Wallace H. Coulter Department of Biomedical Engineering (BME).
All materials in SMARTech are protected under U.S. Copyright Law and all rights are reserved. Such materials may be used, quoted or reproduced for educational purposes only with prior permission, provided proper attribution is given. Any redistribution, reproduction or use of the materials, in whole or in part, is prohibited without prior permission of the author.
Sub-communities within this community
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Department of Biomedical Engineering Seminars, Symposia, and Workshops [9]
Seminars, Symposia, and Workshops hosted by the The Wallace H. Coulter Department of Biomedical Engineering
Collections in this community
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Biomedical Engineering Technical Reports [32]
Papers and articles produced by Dr. Brani Vidakovic's research -
Biomedical Imaging Lab (Minerva Research Group) [210]
Research produced by the Minerva Research Group in the Biomedical Imaging Lab -
Department of Biomedical Engineering Faculty Publications [66]
Papers, Pre/Post-Prints, and Presentations by Faculty in the Department of Biomedical Engineering -
Department of Biomedical Engineering OSP Research Reports [20]
Office of Sponsored Programs research reports by faculty and researchers in the Department of Biomedical Engineering -
Department of Biomedical Engineering Theses and Dissertations [432]
Original work by students in the Department of Biomedical Engineering -
Department of Biomedical Engineering Undergraduate Research Option Theses [125]
Research Thesis Option for Biomedical Engineering Majors
Recent Submissions
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Effects of Microgravity on Visual Impairment and Intracranial Pressure Syndrome
(Georgia Institute of Technology, 2019-02-12)Studying the effects of microgravity on visual impairment and intracranial pressure syndrome. Specifically looking at the combined effects of mechanical stretch and homocysteine. -
Material-Directed Chondrogenic Differentiation Under Mechanical Stimulation
The mechanical properties of scaffolds used to encapsulate stem cells are widely known to help direct the differentiation of those stem cells down different lineages. When studying chondrogenesis, the ability of the scaffold ... -
Exosome-mediated differentiation of adipose-derived mesenchymal stem cells to trabecular meshwork cells
Glaucoma is the second leading cause of blindness and affects over 70 million people worldwide. Intraocular pressure (IOP), a well-established risk factor for primary open angle glaucoma, the most common form of glaucoma, ... -
An examination of the noninflammatory role of astrocytes in glutamate excitotoxicity in SOD1 G93A ALS mouse model
Astrocytes can be found between the vascular and neuronal elements of the central nervous system, where they take up and release molecules in order to maintain a homeostatic microenvironment for optimal neuron growth. ... -
A Biophysical Model of Endothelial Cell Behavior during Cerebral Cavernous Malformation
Cerebral Cavernous Malformations (CCMs) are a collection of enlarged blood vessels with irregular structure in the brain that are caused by a mutation in one of three genes, CCM-1, -2, or -3. For those with CCMs, the ... -
Multi-scale Quantitative Assessment of Apoptosis, Bioenergetics, and Oxidative Stress Molecular Mechanisms in the SOD1 G93A Transgenic ALS Mouse Model
Apoptosis, bioenergetics, and oxidative stress have been implicated in Amyotrophic Lateral Sclerosis (ALS) disease progression; it is unclear as to how the interactions within this highly inter-related triad of categories ... -
Modeling Electrophysiological Dynamics in Transient Deep Brain Stimulation of the Subcallosal Cingulate
Deep brain stimulation (DBS) is a promising investigational treatment for patients with treatment resistant depression (TRD). However, the exact mechanism of action of SCCwm-DBS is unknown and its effects on the electrophysiology ... -
Characterization of Electrodes for Kilohertz Electrical Stimulation
Kilohertz electrical stimulation (KES) induces repeatable and reversible conduction block of nerve activity and is a potential therapeutic option for various diseases and disorders resulting from pathological or undesired ... -
A preliminary study comparing challenging standing and walking balance tasks to discriminate between experts and novices
There are no established techniques to reliably discriminate between groups of healthy individuals based on balance skill. Current balance assessment techniques often fail to detect subtle differences in balance skill, ... -
Hydrogels with magnetic nanoparticles and fluorescent component
The goal of this project is to develop a vehicle for a therapy treatment that increases stem cell-mediated tissue regeneration in bone defects. Tissue engineering has been viewed as a better strategy to repair bone defects ... -
Time Course of Adaptation to a Split-Crank Ergometer
Cycling ergometers have been used in rehabilitation as a way to increase the symmetry in lower limb force output. Adaptation and savings, a property of memory that is characterized by a faster rate of relearning than the ... -
The Effect of Combined Physical and Mental Exertion Prior to using DETECT, a Novel Neuropsychological Test Battery
The purpose of this intervention study is to identify the effect of physical and mental exertion on neuropsychological assessments using the neuropsychological DETECT test in healthy, moderately fit, college-aged students. ... -
Potential therapy against Glioblastoma using Motile Nanocarrier Expressing TRAIL and Azurin
Glioblastoma (GBM) is the most common and aggressive type of gliomas in humans. It is also highly resistant to most treatment methods. Nearly 12,000 people are diagnosed with glioblastoma each year in the United States. ... -
Development of a coronary flow model for aortic valve testing
Transcatheter aortic valve replacement is a promising new technique to treat patients with severe aortic stenosis due to its minimally invasive approach. Unfortunately, higher levels of thrombosis from utilizing this device ... -
Nanoparticle-mediated functional and molecular photoacoustic imaging for assessment of metastatic lymph nodes
(Georgia Institute of Technology, 2018-11-14)Despite advances in prevention, detection, and treatment of cancer, this disease remains the second leading cause of death in the United States. The majority of cancer related deaths are due to metastasis rather than primary ... -
Temporal cathepsin and matrix metalloproteinase activity in tendon extracellular matrix damage
(Georgia Institute of Technology, 2018-08-24)Tendinopathy, or tendon overuse, is one of the most common musculoskeletal disorders affecting athletes, laborers, and aging adults. If left untreated, overuse injury can progress to partial or full-thickness tears that ... -
Engineering an improved cartilage repair strategy combining cells and ECM-derived materials
(Georgia Institute of Technology, 2017-11-13)Osteoarthritis (OA) is the leading cause of disability in the US. The avascularity, low cellularity, and slow proliferation of chondrocytes as well as joint inflammation all limit the regenerative capacity of cartilage. ... -
Microfluidic devices for stiffness dependent enrichment of red blood cell subpopulations
(Georgia Institute of Technology, 2017-11-07)Microfluidic devices were designed, fabricated and tested for enriching red blood cell subpopulations based on their stiffness. First, stiffness dependent margination of red blood cells in high aspect ratio straight ... -
In vivo and in vitro evaluation of an ECM-based OA therapy
(Georgia Institute of Technology, 2017-11-22)Osteoarthritis (OA) is a disease estimated to affect 10-12% of the adult US population and there are currently no clinically proven disease modifying therapies. Micronized dehydrated human amnion/chorion membrane (μ-dHACM) ... -
Investigating differential electrotaxis of glioblastoma and medulloblastoma spheroidal aggregates
(Georgia Institute of Technology, 2017-11-02)Treatment of brain and nervous system cancers remains a daunting clinical challenge, with one of the most common brain malignancies, glioblastoma, incurring a mere 5% five-year survival rate. In the search for new therapeutic ...
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