The Wallace H. Coulter Department of Biomedical Engineering (BME)
The role of the biomedical engineer is to provide answers to problems arising from the study of living systems by employing the methodology and principles of engineering. We are now embarking on the Biomedical Century, and the need for engineers trained in biomedicine is increasing at a tremendous pace.
In September 1997, after an intense planning and review process that involved faculty from both institutions, Georgia Tech joined with Emory University School of Medicine to establish The Wallace H. Coulter Department of Biomedical Engineering (BME).
All materials in SMARTech are protected under U.S. Copyright Law and all rights are reserved. Such materials may be used, quoted or reproduced for educational purposes only with prior permission, provided proper attribution is given. Any redistribution, reproduction or use of the materials, in whole or in part, is prohibited without prior permission of the author.
Sub-communities within this community
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Department of Biomedical Engineering Seminars, Symposia, and Workshops [9]
Seminars, Symposia, and Workshops hosted by the The Wallace H. Coulter Department of Biomedical Engineering
Collections in this community
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Biomedical Engineering Technical Reports [32]
Papers and articles produced by Dr. Brani Vidakovic's research -
Biomedical Imaging Lab (Minerva Research Group) [210]
Research produced by the Minerva Research Group in the Biomedical Imaging Lab -
Department of Biomedical Engineering Faculty Publications [66]
Papers, Pre/Post-Prints, and Presentations by Faculty in the Department of Biomedical Engineering -
Department of Biomedical Engineering OSP Research Reports [20]
Office of Sponsored Programs research reports by faculty and researchers in the Department of Biomedical Engineering -
Department of Biomedical Engineering Theses and Dissertations [509]
Original work by students in the Department of Biomedical Engineering -
Department of Biomedical Engineering Undergraduate Research Option Theses [173]
Research Thesis Option for Biomedical Engineering Majors
Recent Submissions
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Biofilm Matrix Properties in Pseudomonas aeruginosa under Bacteriophage Treatment
Biofilms are a specialized structural formation that some bacterial species form when growing in certain environments. One such environment is the human lung, where the bacteria Pseudomonas aeruginosa forms biofilms that ... -
Dissociable Effect of Stimulus Fluency on Accuracy and Confidence in Perceptual Decision Making
Perceptual decision making relies on collecting evidence from stimuli to make an accurate judgement. The decision is accompanied by a sense of confidence based on the same evidence. Although the accuracy and confidence of ... -
An investigation of the mechanism behind Adjuplex and its effect in adjuvant combinations
This research thesis contributes to the field of biomedical engineering, specifically to the following topics: immunotherapy, drug delivery, and adjuvant-vaccine work. By utilizing RAW-Blue cells to observe IFN-β production, ... -
Ability of Janus Particle as Single Cell Sensor to Immobilize Plasma Cells and Collect Antibody
The method to identify and isolate the proteins is one of the keys to the immunoassay production. However, currently there is no effective way to isolate the protein not only because of limited number of technologies for ... -
Characterizing protein-protein and RNA-protein interactions in fixed cells and tissue
(Georgia Institute of Technology, 2019-10-28)The molecular machinery of the cell is governed by interactions between proteins, DNA, and RNA. For example, innate immune system activation is characterized by the formation and disassociation of protein complexes in a ... -
Enabling precision medicine by integrating multi-modal biomedical data
(Georgia Institute of Technology, 2020-12-15)With the advancement of technologies such as high-throughput sequencing, a massive amount of multi-modal biomedical data has been generated at an unprecedented speed and volume every year. However, extracting information ... -
Tunable Elastomeric Nano-Channels from Guided Fracture for Biopolymer Super Resolution Imaging
(Georgia Institute of Technology, 2019-11-06)This thesis describes the development of a polydimethylsiloxane (PDMS) based micro-, nano-fluidics system compatible with super-resolution imaging to capture and linearize extracted chromatin, for epigenetics studies. ... -
Anatomy of a Joint Sound – Using Joint Acoustic Emissions to Diagnose and Grade Musculoskeletal Disease and Injury
(Georgia Institute of Technology, 2019-11-12)There exists a need for a quantitative, objective measure of joint health status. In this work, a technique for recording the acoustic emissions (AEs) generated during joint flexion and extension was proposed. Analytical ... -
Quasi-periodic patterns of brain intrinsic activity coordinate the functional connections in humans
(Georgia Institute of Technology, 2019-11-12)The brain is a complex self-organizing biophysical system and intrinsically very active. How such intrinsic activity organizes the brain in humans is widely being studied during resting-state using functional magnetic ... -
Computational Modeling of Left Ventricle-Valve Dynamics using a Fluid-Structure Interaction Framework
(Georgia Institute of Technology, 2019-11-12)The left heart (LH) is a key player of the cardiovascular system. Diseases of and associated with the left ventricle (LV)-valve complex account for a large share of cardiovascular disease-related deaths. As accurate and ... -
Engineering cardiac biological pacemaker tissues to dissect source-sink mismatch in the heart
(Georgia Institute of Technology, 2019-10-01)Each and every heartbeat is initiated from, and driven by, the pacemaker cells in the sinoatrial node (SAN). More than 10 billion cardiac myocytes and non-myocytes make up the heart, but remarkably, it takes only a few ... -
Combining Sphingolipidomics and Computational Systems Biology to Study Red Blood Cell Sphingolipid Metabolism in Health and Disease
(Georgia Institute of Technology, 2019-08-27)Liquid chromatography-tandem mass spectrometry-based sphingolipidomics was combined with computational modeling to characterize sphingolipid metabolism in red blood cells and how it is altered in sickle cell disease. ... -
Engineering an aortic valve with cellular and mechanical functionality
(Georgia Institute of Technology, 2019-08-27)Heart valve disease is an increasing clinical burden associated with high morbidity and mortality. Current, valve replacements have a number of risks, such as thrombogenicity and calcification. For pediatric patients, a ... -
Aqueous Two-Phase System Micro-Assays Augmented by Automated Image Analysis
(Georgia Institute of Technology, 2019-11-12)Aqueous two-phase systems (ATPS) are a quirk of thermodynamics, wherein two immiscible solutions separate into stable liquid phases, containing primarily water. Conveniently, some biomolecules partition favorably into one ... -
Design and Validation of a Handheld Probe to Measure Knee Joint Sounds
The goal of this research is to design and validate a system used to record joint sounds measurements that can be collected at home by patients. Wearable and handheld technology allows patients to monitor conditions at ... -
AxoNet: A Deep Learning-based Tool to Count Retinal Ganglion Cell Axons
In this work, we develop a robust, extensible tool to automatically and accurately count retinal ganglion cell axons in optic nerve (ON) tissue images from various animal models of glaucoma. We adapted deep learning to ... -
A Comparison Study on the Effects of Polycaprolactone Degradation Using Different 3D Bio-Printing Technologies
Polycaprolactone (PCL) is a respected polymer for bio-implantation in the field of tissue engineering for scaffolding due to the its compatible and slow bio-degradation properties. While studies have been conducted on the ... -
Gold Nanoparticles Treatment in MCF-7 Spheroid Co-Cultures With Dendritic Cells
In the last decade biomaterials have increasingly been studied as the next generation of immunotherapeutic treatments for their tendency to induce host response against themselves when implanted. Addressing this significant ... -
Force-Signaling Coupling at Single Focal Adhesions
Cell adhesion to extracellular matrices (ECM) is regulated by integrin receptors. After binding to ECM proteins, integrin clustering occurs to form focal adhesion (FA) complexes. These complexes contain proteins that link ... -
The Phenotypic Response of Dendritic Cells to Gold Nanoparticles Treatments
Immunotherapy research has been increasingly investigating the potential of gold nanoparticles (AuNPs). AuNPs pose new benefits in the medical field ranging from diagnostics to diseases treatment. AuNPs’ ability to infiltrate ...
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