Now showing items 1-20 of 129

    • Ab initio Gene Identification in Metagenomic Sequences 

      Zhu, Wenhan; Lomsadze, Alexandre; Borodovsky, Mark (Georgia Institute of TechnologyOxford University Press, 2010)
      We describe an algorithm for gene identification in DNA sequences derived from shotgun sequencing of microbial communities. Accurate ab initio gene prediction in a short nucleotide sequence of anonymous origin is hampered ...
    • Adaptive wavelet estimator for nonparametric density deconvolution 

      Pensky, Marianna; Vidakovic, Brani (Georgia Institute of TechnologyInstitute of Mathematical Statistics, 1999)
      The problem of estimating a density g based on a sample X ₁ X ₂,…,X [subscript n] from p = q ∗ g is considered. Linear and nonlinear wavelet estimators based on Meyer-type wavelets are constructed. The estimators are ...
    • Affine Registration of label maps in Label Space 

      Rathi, Yogesh; Malcolm, James G.; Bouix, Sylvain; Tannenbaum, Allen R.; Shenton, Martha E. (Georgia Institute of TechnologyJournal of Computing, 2010-04)
      Two key aspects of coupled multi-object shape analysis and atlas generation are the choice of representation and subsequent registration methods used to align the sample set. For example, a typical brain image can be labeled ...
    • An analog VLSI model of muscular contraction 

      Hudson, Tina A.; Bragg, Julian A.; Hasler, Paul; DeWeerth, Stephen P. (Georgia Institute of TechnologyInstitute of Electrical and Electronics Engineers, 2003-07)
      We have developed analog VLSI circuits to model the behavior demonstrated by biological sarcomeres, the force generating components of muscle tissue. The circuits are based upon the mathematical description of crossbridge ...
    • ArrayWiki: an enabling technology for sharing public microarray data repositories and meta-analyses 

      Stokes, Todd H.; Torrance, J. T.; Li, Henry; Wang, May D. (Georgia Institute of TechnologyBioMed Central, 2008)
      Background. A survey of microarray databases reveals that most of the repository contents and data models are heterogeneous (i.e., data obtained from different chip manufacturers), and that the repositories provide only ...
    • Assistive Mobile Manipulation for Self-Care Tasks Around the Head 

      Hawkins, Kelsey P.; Grice, Phillip M.; Chen, Tiffany L.; King, Chih-Hung; Kemp, Charles C. (Georgia Institute of Technology, 2014)
      Human-scale mobile robots with arms have the potential to assist people with a variety of tasks. We present a proof-of-concept system that has enabled a person with severe quadriplegia named Henry Evans to shave himself ...
    • An asynchronous architecture for modeling intersegmental neural communication 

      Patel, Girish N.; Reid, Michael S.; Schimmel, David E.; DeWeerth, Stephen P. (Georgia Institute of TechnologyInstitute of Electrical and Electronics Engineers, 2006-02)
      This paper presents an asynchronous VLSI architecture for modeling the oscillatory patterns seen in segmented biological systems. The architecture emulates the intersegmental synaptic connectivity observed in these biological ...
    • Automated smoother for numerical decoupling of dynamic models 

      Vilela, Marco; Borges, Carlos C. H.; Vinga, Susana; Vasconcelos, Ana Tereza R.; Santos, Helena; Voit, Eberhard O.; Almeida, Jonas S. (Georgia Institute of TechnologyBioMed Central, 2007-08)
      Background Structure identification of dynamic models for complex biological systems is the cornerstone of their reverse engineering. Biochemical Systems Theory (BST) offers a particularly convenient solution because its ...
    • Autonomously learning to visually detect where manipulation will succeed 

      Nguyen, Hai; Kemp, Charles C. (Georgia Institute of TechnologySpringer Verlag, 2013-09)
      Visual features can help predict if a manipulation behavior will succeed at a given location. For example, the success of a behavior that flips light switches depends on the location of the switch. We present methods that ...
    • Bacillus anthracis genome organization in light of whole transcriptome sequencing 

      Martin, Jeffrey; Zhu, Wenhan; Passalacqua, Karla D.; Bergman, Nicholas; Borodovsky, Mark (Georgia Institute of TechnologyBioMed Central, 2010)
      Emerging knowledge of whole prokaryotic transcriptomes could validate a number of theoretical concepts introduced in the early days of genomics. What are the rules connecting gene expression levels with sequence determinants ...
    • BAMS Method: Theory and Simulations 

      Vidakovic, Brani; Ruggeri, Fabrizio (Georgia Institute of TechnologyPublished by: Springer on behalf of the Indian Statistical Institute. Article Stable URL: http://www.jstor.org/stable/25053173, 2001-08)
      In this paper we address the problem of model-induced wavelet shrinkage. Assuming the independence model according to which the wavelet coefficients are treated individually, we discuss a level-adaptive Bayesian model in ...
    • Behavioral analysis of anisotropic diffusion in image processing 

      You, Yu-Li; Xu, Wenyuan; Tannenbaum, Allen R.; Kaveh, Mostafa (Georgia Institute of TechnologyInstitute of Electrical and Electronics Engineers, 1996-11)
      In this paper, we analyze the behavior of the anisotropic diffusion model of Perona and Malik (1990). The main idea is to express the anisotropic diffusion equation as coming from a certain optimization problem, so its ...
    • Blind deconvolution of medical ultrasound images: parametric inverse filtering approach 

      Michailovich, Oleg V.; Tannenbaum, Allen R. (Georgia Institute of TechnologyInstitute of Electrical and Electronics Engineers, 2007-12)
      The problem of reconstruction of ultrasound images by means of blind deconvolution has long been recognized as one of the central problems in medical ultrasound imaging. In this paper, this problem is addressed via proposing ...
    • caCORRECT2: improving accuracy and reliability of microarray data in the presence of artifacts 

      Moffitt, Richard A.; Yin-Goen, Qiqin; Stokes, Todd H.; Parry, R. M.; Torrance, James H.; Phan, John H.; Young, Andrew N.; Wang, May D. (Georgia Institute of TechnologyBioMed Central, 2011)
      Background. In previous work, we reported the development of caCORRECT, a novel microarray quality control system built to identify and correct spatial artifacts commonly found on Affymetrix arrays. We have made recent ...
    • Canonical modeling: a review of concepts with emphasis on environmental health 

      Voit, Eberhard O. (Georgia Institute of TechnologyNational Institute of Environmental Health Sciences, 2000-10)
      The article reviews concepts of canonical modeling in the context of environmental health. Based on biochemical systems theory, the canonical approach was developed over the past thirty years and applied to complex systems ...
    • Catch bonds govern adhesion through L-selectin at threshold shear 

      Yago, Tadayuki; Wu, Jianhua; Wey, C. Diana; Klopocki, Arkadiusz G.; Zhu, Cheng; McEver, Rodger P. (Georgia Institute of TechnologyRockefeller University Press, 2004-09)
      Flow-enhanced cell adhesion is an unexplained phenomenon that might result from a transport-dependent increase in on-rates or a force-dependent decrease in off-rates of adhesive bonds. L-selectin requires a threshold shear ...
    • Challenges for the identification of metabolic pathways from time series data 

      Voit, Eberhard O.; Marino, Simeone; Lall, Raman (Georgia Institute of TechnologyBioinformation Systems e.V., 2004-12-23)
    • Characteristics of second harmonic generation of Lamb waves in nonlinear elastic plates 

      Mueller, Martin Fritz; Kim, Jin-Yeon; Qu, Jianmin; Jacobs, Laurence J. (Georgia Institute of TechnologyAcoustical Society of America, 2010-04)
      This paper investigates the characteristics of the second harmonic generation of Lamb waves in a plate with quadratic nonlinearity. Analytical asymptotic solutions to Lamb waves are first obtained through the use of a ...
    • The Chlorella variabilis NC64A Genome Reveals Adaptation to Photosymbiosis, Coevolution with Viruses, and Cryptic Sex 

      Blanc, Guillaume; Duncan, Garry; Agarkova, Irina; Borodovsky, Mark; Gurnon, James; Kuo, Ala; Lindquist, Erika; Lucas, Susan; Pangilinan, Jasmyn; Polle, Juergen; Salamov, Asaf; Terry, Astrid; Yamada, Takashi; Dunigan, David D.; Grigoriev, Igor V.; Claverie, Jean-Michel; Van Etten, James L. (Georgia Institute of TechnologyAmerican Society of Plant Physiologists, 2010-09)
      Chlorella variabilis NC64A, a unicellular photosynthetic green alga (Trebouxiophyceae), is an intracellular photobiont of Paramecium bursaria and a model system for studying virus/algal interactions. We sequenced its 46-Mb ...
    • Collective decision making in bacterial viruses 

      Weitz, Joshua S.; Mileyko, Yuriy; Joh, Richard I.; Voit, Eberhard O. (Georgia Institute of TechnologyBiophysical Society, 2008-09)
      For many bacterial viruses, the choice of whether to kill host cells or enter a latent state depends on the multiplicity of coinfection. Here, we present a mathematical theory of how bacterial viruses can make collective ...