School of Chemistry and Biochemistry
The School of Chemistry and Biochemistry maintains research facilities in the Boggs Chemistry Building and the Institute for Bioengineering and Biosciences. To augment academic departments, a number of "centers" have been formed to nurture interdisciplinary research in a variety of areas, ranging from biotechnology to polymers, microelectronics and manufacturing.
Students, faculty and staff contribute to highly collaborative and interdisciplinary research programs.
All materials in SMARTech are protected under U.S. Copyright Law and all rights are reserved. Such materials may be used, quoted or reproduced for educational purposes only with prior permission, provided proper attribution is given. Any redistribution, reproduction or use of the materials, in whole or in part, is prohibited without prior permission of the author.
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School of Chemistry and Biochemistry OSP Research Reports [270]
OSP research reports by faculty and researchers in the School of Chemistry and Biochemistry -
School of Chemistry and Biochemistry Theses and Dissertations [1509]
Original work by students in the School of Chemistry and Biochemistry -
School of Chemistry and Biochemistry Undergraduate Research Option Theses [51]
Research Thesis Option for Chemistry and Biochemistry Majors
Recent Submissions
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Exploration of copper-catalyzed Grignard cross-coupling between 3-halo-4-alkoxybenzoates and bromoisoprenoids
Allylic functionality, often taking the form of terpenes, is a mainstay of marine natural products. The aryl-allyl connection is particularly common, appearing in several product classes derived from Callophycus serratus, ... -
Analysis and illustration of primary and secondary structures of ribosomal RNA and ribosomal proteins
RiboVision is a collection of applications housed on servers at the Georgia Institute of Technology which serves to facilitate the development of publication-quality diagrams of ribosomal RNA (rRNA) and ribosomal protein ... -
Experimental Predictions of Ribosomal Evolution
(Georgia Institute of Technology, 2022-05-02)Translation and the ribosome are universal and necessary components of biology. Testing the predictions of models that detail the evolution of translation and the ribosome can provide us with a fundamental understanding ... -
Leveraging C-X Bonds for Triggered Eliminations, Alkene Functionalizations, and Intramolecular Cyclizations
(Georgia Institute of Technology, 2022-05-02)Chemists continue to take inspiration from nature when it comes to finding and creating biologically relevant compounds. Two branches of organic synthesis—methodological development and target-oriented syntheses—serve ... -
Exploration of the chemodiversity and microbial composition in marine sponges
(Georgia Institute of Technology, 2022-04-20)The marine sponge holobiont, comprising of the invertebrate eukaryotic sponge animal and the microbial symbionts, is a prolific producer of small organic molecules called natural products. The tremendous structural diversity ... -
Exploring Acceptor-Acceptor Metal Carbenes in The Synthesis of Nitrogen Heteroaromatic Scaffolds
Due to their ubiquitous presence in bioactive molecules, the development of new methodologies for the synthesis of nitrogen heteroaromatic scaffolds is key to the field of organic chemistry. In this thesis, acceptor-acceptor ... -
CHOLESTERIC PHASE OF CHITIN NANOCRYSTALS UNDER CONFINEMENT
(Georgia Institute of Technology, 2022-02-01)Chitin nanocrystals (ChNCs) naturally self-assemble into a “cholesteric” liquid crystalline phase (ChLC) above a critical concentration in water. The helical structure of the ChLC selectively reflects the incident white ... -
HYBRIDIZED NANOSCALE TRANSITION METAL OXIDES AS ANODE MATERIALS FOR LITHIUM-ION BATTERIES
(Georgia Institute of Technology, 2022-01-18)Transition metal oxides (TMOs) are promising anode materials to substitute traditional graphite materials, with high theoretical capacities, high safety, low cost, and wide availability. But the low electronic conductivity ... -
HETEROFUNCTIONAL PARTICLES AS SINGLE CELL SENSORS FOR THE LIVE-CELL ANALYSIS AND QUANTIFICATION OF SECRETED PROTEINS
(Georgia Institute of Technology, 2021-05-04)Identification of individual cells that are actively secreting a specific protein is a challenging proposition due the difficulty to assign secreted cellular products to the specific cell. Two challenges to individual ... -
High-Valent f-Element Imidophosphorane Complexes: Electronic Structure and Reactivity
(Georgia Institute of Technology, 2021-05-01)Traditionally, lanthanides exist mostly in the trivalent state in solution with a few exceptions: some divalents (samarium, europium, thulium, ytterbium) and one tetravalent (cerium). Praeseodymium and terbium were predicted ... -
Dancing with Light: Discrete Pi-Conjugated Chromophores for Solar Fuel Cell and Electrochromic Applications
(Georgia Institute of Technology, 2021-04-28)Molecular engineering plays a pivotal role in answering fundamental scientific questions aimed at understanding the relationship between a material and its potential technological application. This dissertation focuses on ... -
REDOX-ACTIVE LIGAND-INDUCED RADICAL REACTIVITY AT HIGH-VALENT OXORHENIUM AND OXOVANADIUM COMPLEXES
(Georgia Institute of Technology, 2021-04-28)Metal-oxyl radicals might be the active species in many important oxygen-atom transfer and H-atom abstraction processes, ranging from industrial petroleum processing to biological detoxification, to energy conversion and ... -
Design, Synthesis, and Characterization of Electron Transporting DPP-based Copolymers for Application in Organic Electronics
(Georgia Institute of Technology, 2021-05-01)The complete design, synthesis, characterization, and electrical performance of n-type donor-acceptor polymers based on diketopyrrolopyrrole (DPP) moieties was conducted for application in OPVs, OFETs, and OECTs. First, a ... -
MICROPOROUS SPIROCYCLIC POLYMERS FOR MEMBRANE SEPARATIONS OF CRUDE OIL MIXTURES
(Georgia Institute of Technology, 2021-04-26)The fractionation of crude oil mixtures via distillation is a large-scale, energy-intensive process. Membrane materials can avoid phase changes in such mixtures and thereby reduce the energy intensity of these thermal ... -
The design and application of functional enyne reagents in metathesis polymerization
(Georgia Institute of Technology, 2021-04-19)Ring-opening metathesis polymerization (ROMP) using Grubbs-type initiators has become a widespread polymerization technique due to its remarkable functional group tolerance and reliability. This has enabled the synthesis ... -
Developing novel mass spectrometry-based approaches to globally investigate protein glycosylation
(Georgia Institute of Technology, 2021-04-07)Glycosylation is one of the most common and essential protein modifications in cells. It plays a critical role in regulating protein folding, trafficking, and stability, and is involved in a wide range of cellular events ... -
MS-Based Chemical Proteomics Studies of Extracellular Glycoproteins: Identification, Quantification, and Dynamics
(Georgia Institute of Technology, 2021-03-24)Extracellular proteins, including cell-surface and secreted proteins, play crucial roles in cell-cell communication, cell-matrix interactions, and the regulation of most extracellular biological processes. The majority of ... -
Characterization of a Novel Dynamic Combinatorial Depsipeptide System with Implications for the Origin of Biopolymers
(Georgia Institute of Technology, 2021-02-15)Proteins are a class of functional macromolecules whose components, amino acids, are thought to have been present on the ancient Earth—long before biology inhabited the planet. However, the orderly association of these ... -
Lipid Biomarker Alterations Following Mild Traumatic Brain Injury
(Georgia Institute of Technology, 2021-01-22)The work presented in this thesis highlights the current state of biomarker research for traumatic brain injury (TBI) and seeks to investigate the potential of novel lipid biomarkers for TBI. Awareness and research interest ... -
Applications of High-resolution Mass Spectrometry and Matrix-assisted Laser Desorption/Ionization Mass Spectrometry Imaging-based Non-targeted Metabolomics in Biomarker Discovery
(Georgia Institute of Technology, 2021-01-19)Mass Spectrometry (MS) is the most commonly used technology in metabolomics studies. The high sensitivity of MS enables the detection of low abundance metabolites that are below the detection threshold of other analytical ...