• Login
    View Item 
    •   SMARTech Home
    • Undergraduate Research Opportunities Program (UROP)
    • Undergraduate Research Option Theses
    • View Item
    •   SMARTech Home
    • Undergraduate Research Opportunities Program (UROP)
    • Undergraduate Research Option Theses
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Thoracic Aorta Displacement and Strain Analysis Using Spiral Cine DENSE MRI

    Thumbnail
    View/Open
    VALDMAN-UNDERGRADUATERESEARCHOPTIONTHESIS-2017.pdf (641.2Kb)
    Date
    2017-12
    Author
    Valdman, Melissa Elizabeth
    Metadata
    Show full item record
    Abstract
    Aneurysms are the 18th most common cause of death in the United States, and patients with connective tissue disorders are at particularly high risk of developing these lesions. Understanding more about the structural and biological properties that play a role in the formation of aneurysms could be vital to their early detection and prevention. In this study, we compare displacement and strain data from six patients who have connective tissue disorders (e.g., Marfan Syndrome, Loeys-Dietz Syndrome, or Ehlers-Danlos) and eight patients with healthy aortas using spiral cine DENSE MRI in order to differentiate the mechanical properties of healthy vs. diseased aortas and to understand the properties associated with different stages of aneurysm formation. We predict that patients with connective tissue disorders will demonstrate larger total displacement and strain along the aortic wall. These results will help differentiate the mechanical properties of healthy aortas and aortas associated with connective tissue disorders, as well as understand the properties associated with different stages of aneurysm formation.
    URI
    http://hdl.handle.net/1853/60344
    Collections
    • Department of Biomedical Engineering Undergraduate Research Option Theses [214]
    • Undergraduate Research Option Theses [862]

    Browse

    All of SMARTechCommunities & CollectionsDatesAuthorsTitlesSubjectsTypesThis CollectionDatesAuthorsTitlesSubjectsTypes

    My SMARTech

    Login

    Statistics

    View Usage StatisticsView Google Analytics Statistics
    facebook instagram twitter youtube
    • My Account
    • Contact us
    • Directory
    • Campus Map
    • Support/Give
    • Library Accessibility
      • About SMARTech
      • SMARTech Terms of Use
    Georgia Tech Library266 4th Street NW, Atlanta, GA 30332
    404.894.4500
    • Emergency Information
    • Legal and Privacy Information
    • Human Trafficking Notice
    • Accessibility
    • Accountability
    • Accreditation
    • Employment
    © 2020 Georgia Institute of Technology