School of Chemistry and Biochemistry Theses and Dissertations
Original work in partial fulfillment of a graduate degree in the School of Chemistry and Biochemistry
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Recent Submissions
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Effect of titanium dioxide nanoparticle on the redox regulatory network of cells
(Georgia Institute of Technology, 2015-04-27)The extensive industrial and commercial use of titanium dioxide nanoparticles (TiO2 NPs) in paints, cosmetics, and as food coloring additives is associated with high levels of TiO2 NPs released into the environment and ... -
Organic donor-acceptor chromophore-catalyst assembly for solar fuels
(Georgia Institute of Technology, 2015-01-12)In this thesis, a novel chromophore-catalyst molecular assembly is synthesized in the pursuit of affecting rapid water oxidation driven by light. The compound is inspired by previous work done in the lab of John R. Reynolds ... -
Characterization of DNA duplex structure, stability and formation kinetics in a eutectic solvent and its aqueous mixtures
(Georgia Institute of Technology, 2015-02-06)In this work, properties and behavior of DNA oligonucleotides in a non-aqueous eutectic comprised of glycerol and choline chloride mixed at varying ratios, as well as aqueous mixtures of the eutectic are explored. Physical ... -
Numerical methods for chemical analysis of complex surfaces
(Georgia Institute of Technology, 2018-07-25)Temperature programmed desorption (TPD) is a classic surface science experiment that provides information regarding gas adsorption thermodynamics and desorption kinetics. Conventional TPD data analysis methods are inadequate ... -
Novel (homo-)Nazarov approaches to complex polycycles and application to bioactive targets
(Georgia Institute of Technology, 2018-07-25)Complex carbocycles and heterocycles make up a large majority of natural product scaffolds and active pharmaceutical ingredient cores. As a result of this, developing methods to obtain such scaffolds in new, greener, and ... -
Materials for next-generation lithography: Crosslinked molecular resists and photo-patternable underlayers
(Georgia Institute of Technology, 2018-07-25)As feature sizes on integrated circuits (computer chips) continue to decrease in accordance with Moore’s Law, new technologies are needed to maintain pace. Next-generation lithographic techniques, including extreme ultraviolet ... -
Work function tuning of electrode materials with small molecule surface modifiers
(Georgia Institute of Technology, 2018-07-31)Energy level alignment at metal/organic interfaces plays a critical role in charge transport across the interfaces within organic and optoelectronic devices. To control the barriers to injection/collection, dipolar surface ... -
Chemical and genetic modification of virus-like particles for applications in vaccine design and drug delivery
(Georgia Institute of Technology, 2018-05-29)Virus-like particles (VLPs) are multi-subunit protein assemblies that self-assemble into homogenous particles with periodic structure, making them ideal candidates for applications in biomedicine. This dissertation will ... -
Rovibronic spectroscopy of sympathetically cooled CaH+
(Georgia Institute of Technology, 2018-05-18)CaH+ is an astrophysically relevant molecule with proposed applications in fundamental physics. We use CaH+ co-trapped with Doppler cooled Ca+ to perform spectroscopy using two-photon photodissociation with a frequency ... -
Synthesis, structure, and reactivity studies of ketenylidene, carbide, carbynoid, carbenoid, and tetrazolyl complexes of gold
(Georgia Institute of Technology, 2018-05-22)Chapter 1 gives a brief introduction to the topic of main group element bridged gold(I) clusters, the effects of aurophilic attraction on gold(I) cluster formation, and gold(I) carbene chemistry. An isolobal analogy is ... -
Fragmentable bicyclo[3.3.1]nonane cationic materials and their applications to nucleic acid delivery and antimicrobial function
(Georgia Institute of Technology, 2018-05-23)The goal of the research reported in this thesis is to investigate reversible bond formation in bicyclo[3.3.1] system through anchimeric assistance and use that as building blocks to assemble functional cationic materials, ... -
Aminolytic synthesis and ferromagnetic resonance of cobalt and manganese based spinel ferrite nanoparticles
(Georgia Institute of Technology, 2018-05-17)Magnetic ferrite nanoparticle is a potential material in a number of fields and designing of such applications requires the fine-tuning of magnetic properties through synthesis by chemical composition and dimensional ... -
Symmetry-adapted perturbation theory for organocatalysis
(Georgia Institute of Technology, 2018-05-03)Functional-group and atomic partitions of symmetry-adapted perturbation theory (SAPT) were used, for the first time, to analyze non-covalent interactions thought to influence the selectivity of the Houk-List mechanism for ... -
Development of intermolecular C-H functionalization methods for acceptor-acceptor diazo compounds
(Georgia Institute of Technology, 2018-05-11)Given the recent progress made with donor-acceptor (D-A) carbene C-H functionalization, as well as the functional diversity of acceptor-acceptor (A-A) carbenes, surprisingly little investigation has been conducted by the ... -
Titanium dioxide nanoparticles: Protein adsorption and cellular interactions
(Georgia Institute of Technology, 2017-07-31)Titanium dioxide nanoparticles are used in many applications from photocatalysis to pigmentation. Their presence in commercial products such as paints, sunscreens, cosmetics, and food motivates interest in understanding ... -
Multidimensional statistics metric in biological data analysis
(Georgia Institute of Technology, 2017-07-26)Sepsis, a serious body’s response to infection, is still a leading cause of death around the world. Appropriate treatment, however, can take more than three days for the clinical lab to determine. Board-spectrum antibiotics ... -
A computational investigation into the third-order nonlinear optical properties of cyanine-like polymethines for all-optical switching applications
(Georgia Institute of Technology, 2017-07-21)Cyanine-like polymethines have recently attracted renewed attention for their potential as materials to realize all-optical switching applications by demonstrating large real and small imaginary parts of the third-order ... -
A Pedot by any other name: Tuning the electroactivity of dioxy-heterocycles for redox and solid state applications
(Georgia Institute of Technology, 2017-07-26)Redox active conjugated polymers are used in a variety of applications including electrochromism, charge storage, plasmonic resonance tuning, and electrochemical transistors. This thesis describes the development of ... -
The effects of nanoparticle properties on biological imaging and photothermal cancer treatment
(Georgia Institute of Technology, 2017-06-22)Over the past two decades, gold nanoparticles (AuNPs) have emerged as promising tools for biomedical applications. Their unique optical properties enable sensitive detection and effective treatment strategies. Additionally, ... -
Tailoring functional Π-conjugated polymers and molecules for organic photovoltaic applications
(Georgia Institute of Technology, 2017-05-12)The field of organic photovoltaics (OPVs) has developed into an active research topic in applied polymer, materials, and chemical sciences over the past decade due to the continuous improvement in device performance. The ...
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