• An investigation into the multiple Type VI Secretion Systems of Enterobacter cloacae 

  Wilson, Ashley

  Enterobacter cloacae is a Gram-negative, opportunistic bacterial pathogen that is commonly acquired by patients in hospitals. The Type VI Secretion System (T6SS) is a harpoon-like apparatus that injects toxins into the ...

• Ischemia induces changes in SOD activity and neuromuscular regeneration 

  Aliya, Berna

  Critical limb ischemia (CLI) is characterized as a neuromuscular disorder of aging that develops due to an occlusion of blood flow to the affected lower limbs. Following ischemic injury, disruption of vasculature interrupts ...

• Single particle cryo-EM structure elucidation of a Photosystem II complex mimicking a critical step in photoinhibition 

  Espy, Carolann Lindsay

  Photosystem II (PSII) is an essential protein in the photosynthetic process that houses the oxygen evolution center, which is responsible for producing most of the oxygen in the atmosphere. In order to better understand ...

• Investigating effect of oxidative stress during in vitro myogenic differentiation 

  Kang, Innie

  Stem cell research has been developing new ways to understand the mechanism behind aging in muscles as well as ways to prevent debilitating symptoms of it. In this study, Pax7-CreER-Sod1 floxed cells were used to model ...

• Investigation of the Role of Hyaluronan in Neural Crest Cell Migration, Adhesions, and Morphology 

  Mykyten, Kathryn A.

  Xenopus laevis neural crest cells are a common and useful model for studying cell migration in many contexts, including developmental biology, cancer, and other basic science. This study examines the role hyaluronan (also ...

• Optogenetic Manipulation of Caenorhabditis elegans Pharyngeal Muscles Inhibit Food Consumption 

  Clever, Faye

  Obesity, a complex condition that arises from a host of interwoven environmental, cultural, social, and genetic factors, is associated with many devastating diseases. However, resolving the intricacies of obesity-related ...

• Impact of parrotfish predation on coral health: changes in microbiome and pathogen defense 

  Towner, Alexandra

  Coral reefs are in rapid decline, and it is imperative to study reef community interactions in order to mitigate and reverse this trajectory. This study explores the relationship between corals and parrotfish, investigating ...

• Activity Budget and Spatial Behavior of the Emerald Tree Boa Corallus batesii 

  Sethna, Jadyn M.

  Corallus batesii is a boid snake native to the Amazon basin. C. batesii was declared a distinct species from its sister species in 2009. Because of this recent taxonomic shift, much of the research on the basic biology and ...

• Probing the Dynamic Nature of Mycobacterial Heme Homeostasis 

  Hale, Owen Francis

  Mycobacterium tuberculosis is responsible for more human deaths every year than any other bacterium. In order to establish an infection and cause disease, M. tuberculosis requires the nutrient heme. Heme is essential for ...

• Salivary Micro RNA as a Biomarker for Concussion Symptoms in Pediatric Patients 

  Bryant, Graham G.

  This research project employs an untargeted approach using RNA sequencing to identify miRNA in saliva following a traumatic brain injury, specifically a concussion, to better understand how acute brain injuries can be ...

• Pruritic Activity and Neurogenic Inflammation with S. aureus δ-toxin in Atopic Dermatitis 

  Olsen, Victoria

  This study investigates how toxins secreted from Staphylococcus aureus, such as δ-toxin, can produce pruritis and initiate neurogenic inflammation to help characterize the cutaneous neural reaction to S. aureus colonization ...

• USING ASCORBIC ACID AND HIGH SALINITY TO EXTEND THE VIABILITY OF PROALES SIMILIS (ROTIFERA) DIAPAUSING EGGS 

  Brashear, Jillian

  Rotifers are sensitive indicators of environmental conditions and serve as model organisms for assessing toxicity. It is understood that rotifer cysts (diapausing eggs) are convenient for toxicity assessment because they ...

• Uncovering the peatland root microbiome: Environmental factors shaping microbial community structure 

  Verlander, Sarah Elizabeth

  This study examines the effects of simulated whole-ecosystem warming and elevated levels of carbon dioxide on the microbial communities within the root-soil microbiomes of vascular plants in peatlands. Root samples obtained ...

• Does short term upper limb immobilization affect inter-limb transfer of sequence-specific motor skill? 

  Krakovski, Maria A.

  Previous research has demonstrated that short-term limb immobilization leads to a decrease in corticospinal excitability and a subsequent increase in the capacity for long term potentiation, the neural mechanism underlying ...

• The Effects of Ocean Acidification on Molt Rate and Carapace Area in Juvenile Dungeness Crabs (Cancer magister) 

  Reinhardt, Emma

  Ocean acidification, the consequence of atmospheric CO2 dissolving in the ocean to form carbonic acid, is rapidly intensifying. A wealth of marine wildlife is known to be vulnerable to the expected drop in pH, including a ...

• Time of day predicts the activity budget in the Emerald Tree Boa (Boidae: Corallus batesii) across multiple behaviors 

  Berry, Savannah Margaret

  Exploring the spatial ecology and behavior of organisms is essential to understand an organism’s niche and how to better accommodate animals that are kept in captivity (Ross et al., 2011; Plowman, 2003). Emerald Tree Boas ...

• scRNA-seq dropouts serve as a signal for tissue heterogeneity in autism spectrum disorder 

  Spencer, Collin

  Analysis of single-cell RNA-sequencing (scRNA-seq) data is plagued by dropouts, zero counts for mRNA transcripts due to low mRNA in individual cells and inefficient mRNA capture. Dropouts are traditionally treated as an ...

• Transcriptomic profiling of human cells destined for therapeutic applications 

  Medrano Trochez, Camila (Georgia Institute of Technology, 2021-03-21)

  Cell therapy is a growing field as many diseases are still untreatable. Potential applications of cell therapies include treating cancers, autoimmune disease, urinary problems, and infectious disease, rebuilding damaged ...

• BIOFERTILIZERS FOR SUSTAINABLE AGRICULTURE: ISOLATION AND GENOMIC CHARACTERIZATION OF NITROGEN-FIXING BACTERIA FROM SUGARCANE 

  Medina Cordoba, Luz Karime (Georgia Institute of Technology, 2020-01-03)

  The goal of my thesis research was to explore the use of bacterial biofertilizers, as an alternative or complementary approach to chemical fertilizers, in support of more sustainable agricultural practices. To this end, ...

• MOLECULAR MECHANISMS OF RNA-MEDIATED DNA REPAIR AND MODIFICATION 

  Meers, Chance (Georgia Institute of Technology, 2020-01-13)

  Genomic stability is essential in maintaining the accurate inheritance of genetic material from mother to daughter cell. However, endogenous and exogenous stresses are continuously attacking and damaging genetic information. ...

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