• Developing Tools to Monitor Vibrio cholerae Type VI Secretion During Range Expansion on Solid Surfaces 

  Ng, Siu Lung Lung

  The waterborne bacterium Vibrio cholerae causes the fatal cholera diarrhea, and thrives in aquatic environments attached to chitinous surfaces with other bacteria. V. cholerae has been used to study natural competence, ...

• Dominance and exhibit use in captive African elephants (Loxodonta africana) 

  Iacono, Jennifer (Georgia Institute of Technology, 2018-12-06)

  The African elephant (Loxodonta africana) is a highly social species that typically lives in large, matrilineal family groups called herds which contain a linear dominance hierarchy between the adult females. Management ...

• Microbiome community change in the guts of marine fish: feeding and life stage transition as significant organizing factors 

  Parris, Darren J. (Georgia Institute of Technology, 2018-11-08)

  All animals harbor microbial communities (microbiomes) that play vital roles in host health, development, behavior, and evolution. Determining the processes that regulate microbiome diversity and function is therefore a ...

• Blood eQTL detection in structured populations and its application to interpretation of genetic association studies 

  Zeng, Biao (Georgia Institute of Technology, 2018-11-09)

  Expression QTL (eQTL) detection has emerged as an important tool for unravelling the relationship between genetic risk factors and disease or clinical phenotypes. Most studies focus on analyses predicated on the assumption ...

• Genomic basis of evolutionary radiation in Lake Malawi cichlids 

  Patil, Chinar (Georgia Institute of Technology, 2018-11-09)

  Understanding the genomic basis and origin of phenotypic variation is one of the fundamental questions of biology. Evolutionary radiations characterized by a range of natural phenotypic variants between genetically closely ...

• Effects of macroalgal versus coral reef dominance on coral survival, chemical defense, and microbiomes 

  Beatty, Deanna S. (Georgia Institute of Technology, 2018-10-24)

  Coral reefs are among the earth’s most biodiverse and productive ecosystems, but are undergoing precipitous decline due to coral bleaching and disease following thermal stress events, which are increasing in frequency and ...

• Regulation of the type VI secretion system in environmental isolates of vibrio cholerae 

  Hoffmann, Tobias (Georgia Institute of Technology, 2017-12-14)

  Vibrio cholerae is a human pathogen that causes the severe diarrheal disease cholera, but can also inhabit aquatic environments. The type-VI secretion system (T6SS) is a macromolecular contractile machine that injects ...

• Predation, competition, and facilitation on tropical reefs: implications for corals as reefs degrade  

  Clements, Cody Shane (Georgia Institute of Technology, 2017-11-13)

  Tropical coral reefs are among the most diverse and productive ecosystems on Earth, but reefs worldwide have experienced dramatic declines in coral and often transitioned from coral- to macroalgal dominance. As local and ...

• Dissecting the role of linker histone H1 variants in embryonic stem cells 

  Ho, Po-Yi (Georgia Institute of Technology, 2017-08-28)

  To further dissect the role of linker histone H1 in embryonic stem cells (ESCs), here, we have utilized a functional reconstitution approach to identify the regions of H1 proteins that are important to mediate neurite ...

• Mitochondrial Dysfunction in Chronic Limb Ischemic Myopathy 

  Kim, Do Young Young

  Critical limb ischemia (CLI), the most advanced clinical manifestation of peripheral arterial disease (PAD), is associated with cycles of ischemia and reperfusion (I/R) that are thought to compromise the bioenergetics of ...

• In-Situ Water Quality Monitoring for Resource-Constrained Areas 

  Johnson, Ann E

  Water-borne pathogens and unsafe water supplies are the cause of death for 1.7 million people every year [1]. Many of these people live in the developing world, where it can be difficult to manage water safety. The World ...

• Gastrointestinal Motility: Kinematic Properties of Segmentation Contraction 

  Lamarca, Morgan

  The kinematic processes of the small intestine play integral roles in overseeing the digestion and transportation of food throughout the gastrointestinal tract. Specifically responsible for governing the flow and digestion ...

• Catalytic abilities of the Schistosoma mansoni hammerhead ribozyme with mutated substrates in ice 

  Calvird, Audrey

  The synthesis of biomolecules in an environment similar to a pre-biotic Earth within the field of evolutionary chemistry has applications in understanding abiogenesis and the evolution of early biological systems on Earth. ...

• Generalizing Disease Associations to Non-Studied Populations 

  Patel, Kane

  This study determines whether risk allele frequencies (RAFs) for common diseases can be generalized in genome wide association surveys (GWAS) that are done in different populations other than the original study population. ...

• Genetics of Captive Naked Mole-Rat Populations 

  Groh, Amy M (Georgia Institute of Technology, 2015-06-30)

  The evolution of highly social behavior (eusociality) represents one of the major transition points in evolutionary history. Naked mole-rats (NMRs), Heterocephalus glaber, are one of the few known eusocial mammals, meaning ...

• Fish response to macroalgal removal 

  Lin, Cara

  Coral reefs are rapidly degrading into macroalgae dominated systems sustained through positive feedback loops. Macroalgae can harm corals directly via competition and indirectly via suppression of recruitment and increasing ...

• K-mer based data structures and heuristics for microbes and cancer 

  Huang, Cai (Georgia Institute of Technology, 2018-05-15)

  Recent technological advances allow for high throughput profiling of biological systems in a cost-efficient manner. The low cost of data generation is leading us to the “big data” era and the availability of big data ...

• Understanding pathways regulating liver versus pancreas fate decision and beta-cell regeneration 

  Xu, Jin (Georgia Institute of Technology, 2017-08-02)

  The liver and pancreas originate from common endodermal progenitors in early development. It has been shown that Bone morphogenetic protein 2b (Bmp2b) signaling is essential for determining the fate of these bipotential ...

• Applied bioinformatics for exploring diversity patterns in meta-omic data 

  Ranjan, Piyush (Georgia Institute of Technology, 2018-04-25)

  This thesis explores the utility of applied bioinformatic approaches to better understand sequence space and phylogenetic diversity in meta-omic clinical and environmental datasets. In three chapters, the thesis describes ...

• Investigating ice slurry’s perceived mechanical abrasive quality to increase pathogen reduction on poultry during immersion chilling 

  Richter, Stephanie (Georgia Institute of Technology, 2018-04-26)

  The poultry industry is an integral part of Georgia’s economy, accounting for more than half of the state’s agricultural output. In Georgia, more than 20 million pounds of broiler meat are produced daily. Poultry processing ...

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