• Natural competence and Type VI Secretion in Vibrio cholerae 

  Bernardy, Eryn (Georgia Institute of Technology, 2016-07-22)

  The waterborne bacterium Vibrio cholerae, responsible for epidemics of cholera diarrhea, associates with the human gut and with chitinous surfaces in aquatic reservoirs. Prior studies of two clinical V. cholerae isolates ...

• TRANSLATIONAL BIOINFORMATICS FOR PERSONALIZED MEDICINE AND INTEGRATIVE BIOLOGY: Data Integration, Extraction, Knowledge Discovery, and Visualization 

  Uppal, Karan (Georgia Institute of Technology, 2015-10-13)

  This thesis focuses on developing a computational framework to support the Precision Medicine Initiative. The newly developed tools and algorithms use machine learning, text mining and visualization techniques for extracting ...

• Functional significance of sequence variation among miR-200/205 families of miRNAs in ovarian cancer 

  Jabbari, Neda (Georgia Institute of Technology, 2015-07-10)

  MicroRNAs are short non-coding RNAs that regulate large suites of target genes. A family of miRNAs known as the miR-200 is implicated in the epithelial-mesenchymal/ mesenchymal-epithelial transition (EMT/MET), a process ...

• Microbes in the atmosphere: prevalence, species composition, and relevance to cloud formatio 

  De Leon, Natasha Isabel (Georgia Institute of Technology, 2015-07-14)

  The composition and prevalence of microorganisms in the upper troposphere and their role in aerosol-cloud-precipitation interactions represent important, unresolved questions for biological and atmospheric sciences. Most ...

• Functional Analysis Of The Inhibition Of Topoisomerase II Alpha By Linker Histone H1 

  Hamdan, Hiba (Georgia Institute of Technology, 2014-07-02)

  In higher eukaryotes, DNA is progressively packaged into chromatin. In these varying levels of compaction, linker histone H1 is a key player for mediating chromatin folding. As a result, linker histone H1 is involved in ...

• Establishing a Working Protocol for Plasmid Cloning and shRNA Design in Endogenous Brachionus manjavacas Gene TRP7 

  Krishnappan, Sharadha (Georgia Institute of Technology, 2016-07-18)

  Current transfection protocol in rotifers only allows for temporary transfection within rotifers and does not allow for the continuous knockdown of endogenous genes, thereby inhibiting the possibility of observing long-term ...

• Morphological Variation in Hemiphractus Fasciatus (Anura: Hylidae: Hemiphractinae) 

  Martin, Kathryn G. (Georgia Institute of Technology, 2016-07-18)

  We describe morphological variation within the species Hemiphractus fasciatus, with special focus on populations in Panama, and determined the two allopatric populations are morphologically distinct, suggesting that there ...

• Effects on the Pocillopora verrucosa microbiome when in contact with macroalgae under ocean acidification 

  Gantt, Shelby (Georgia Institute of Technology, 2016-07-18)

  Hard coral cover is in decline and this decline has generally coincided with macroalgal proliferation in coral reefs. Coral degradation can be caused by many variables but this study is focused on potential degradation due ...

• Improving algorithms of gene prediction in prokaryotic genomes, metagenomes, and eukaryotic transcriptomes 

  Tang, Shiyuyun (Georgia Institute of Technology, 2016-04-04)

  Next-generation sequencing has generated enormous amount of DNA and RNA sequences that potentially carry volumes of genetic information, e.g. protein-coding genes. The thesis is divided into three main parts describing i) ...

• Epigenetics in social insects 

  Glastad, Karl M. (Georgia Institute of Technology, 2016-01-14)

  Virtually all multicellular organisms are capable of developing differently in response to environmental variation. At the molecular level, such developmental plasticity requires interpretation and perpetuation of ...

• The assembly of protist communities: Understanding drivers of historical contingency and causes and consequences of biodiversity 

  Pu, Zhichao (Georgia Institute of Technology, 2015-04-06)

  Understanding mechanisms regulating the assembly of ecological communities is a major goal of community ecology. I combined experimental and theoretical approaches to investigate the influences of various ecological factors ...

• Bacterial iron and manganese reduction driven by organic sulfur electron shuttles 

  Cooper, Rebecca Elizabeth (Georgia Institute of Technology, 2015-04-08)

  Dissimilatory metal-reducing bacteria (DMRB) play an important role in the biogeochemical cycling of metals. DMRB are unique in that they possess the ability to couple metal reduction with their metabolism. Microbial ...

• Role of linker histone H1 in epigenetic regulation of pluripotency genes and Hox genes 

  Zhang, Yunzhe (Georgia Institute of Technology, 2014-04-04)

  Linker histone H1 plays a key role in facilitating folding of higher order chromatin structure. Previous studies have shown that deletion of three somatic H1 subtypes together leads to embryonic lethality and that H1c/H1d/H1e ...

• Changes in Nutrient Dynamics in the Gulf of Mexico due to Increase in Mississippi River Flow 

  Taylor, Anna (Georgia Institute of Technology, 2016-01-25)

  The Gulf of Mexico underwent multiple environmental changes in 2010 and 2011, including the Deepwater Horizon oil spill and a large in increase of freshwater input from the Mississippi River. Both of these events had the ...

• The Effect of Environmental Factors on Bacteria Associated with Sphagnum Mosses 

  Sexton, William Kyle (Georgia Institute of Technology, 2016-01-25)

  Sphagnum peat mosses play an important role in the global carbon cycle by sequestering carbon as biomass thorough photosynthesis. Biodegradation in the northern peatlands is slow in part due to acidic and nutrient-poor ...

• Finding Food in an Aquatic Desert: How cruising copepods detect their next phytoplankton meal 

  Taylor, Jazmyne Z. C. (Georgia Institute of Technology, 2016-01-25)

  Copepods exist in an aquatic food desert where finding food is difficult given the constraints of their environment. They live in a three dimensional world and must filter 106 times their own body volume to cover their ...

• Factors that Increase the Efficiency of DNA Repair when Using Transcript RNA as a Template 

  Skulskaya, Olexandra (Georgia Institute of Technology, 2016-01-25)

  Interaction with various chemicals and environmental agents can cause damages to DNA. In this study, we particularly focus on double stranded breaks (DSBs) and a repair mechanism that uses transcript RNA to repair the ...

• From rivers to natural gas: The influence of allochthonous inputs on marine nitrogen fixation and the carbon cycle 

  Weber, Sarah C. (Georgia Institute of Technology, 2015-12-04)

  The Western Tropical North Atlantic (WTNA) was once thought to be a net source of carbon dioxide (CO₂) to the atmosphere, but recent studies have shown that this Amazon River influenced region may actually act as a net ...

• Sustainable tilapia feed derived from urban food waste 

  Chaddick, Justin Garrett (Georgia Institute of Technology, 2015-12-08)

  Finding an alternative to fishmeal and fish oil in animal feeds has been a topic of increasing interest due to the pressures being put on the ocean’s fisheries and the increasing world demand for animal protein. An ...

• Computational tools for the analysis of biological networks in plants 

  Das, Abhiram (Georgia Institute of Technology, 2015-08-20)

  This thesis presents research associated to phenotyping of plants by applying informatics techniques which includes databases, web technologies, image processing and feature measurements of 2D and 3D images. The thesis ...

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