School of Biological Sciences
In the summer of 2016, the School of Biology and the School of Applied Physiology were combined into a new School of Biological Sciences.
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Sub-communities within this community
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Center for the Study of Systems Biology (CSSB) [107]
Systems Biology seeks to understand how complex living systems interact with each other to aid in the diagnosis and treatment of disease
Collections in this community
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School of Biology Faculty Publications [227]
Papers, Pre/Post-Prints, and Presentations by Faculty in the School of Biology. -
School of Biology OSP Research Reports [65]
Office of Sponsored Programs research reports by faculty and researchers in the School of Biology -
School of Biology Seminar Series [4]
Weekly seminars that cover research across the breadth of the biological sciences -
School of Biology Theses and Dissertations [410]
Original work in partial fulfillment of a graduate degree in the School of Biology. -
School of Biology Undergraduate Research Option Theses [114]
Research Thesis Option for Biology Majors
Recent Submissions
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Decoding Disease Persistence in Pediatric Acute Lymphoblastic Leukemia One Single Cell at a Time
In order to understand the biological and molecular mechanisms underlying disease resistance to therapy in pediatric acute lymphoblastic leukemia (ALL), we performed an investigation utilizing single-cell RNA-sequencing ... -
Development of a Wireless, Commercial Electromyography System for Use in Athletics and Physical Therapy
Electromyography is a muscle activity recording technique that is not often used in a clinical setting due to difficulties in reproducibility. In this paper I aim to create a wireless, wearable system for electromyography. ... -
Ecological Community Assembly in the Face of Anthropogenic Environmental Changes
(Georgia Institute of Technology, 2019-11-11)Anthropogenic environmental changes, such as increased nitrogen (N) deposition, changes in precipitation regimes, and habitat loss and fragmentation, are known to affect Earth’s ecosystems. Understanding mechanisms regulating ... -
QUANTITATIVE METHODS TO UNDERSTAND REPRODUCTIVE ISOLATION THAT CONTRIBUTE TO SPECIATION
(Georgia Institute of Technology, 2020-10-29)Ever since Darwin’s qualitative theory of the origin of species, there is growing demand for quantitative methods to study mechanisms underlying the speciation process. One key component towards new species formation is ... -
Bioinformatic platforms and methods for worldwide polygenic risk scores
(Georgia Institute of Technology, 2020-08-20)Genetic diversity underpins much of observed human phenotypic diversity and plays an important role in human health and disease. This dissertation is focused on exploring the genetic architecture of phenotypic diversity ... -
Public Health Informatics - Strategy and Decision Modeling
(Georgia Institute of Technology, 2019-08-21)My research is composed of three studies focused on providing decision modeling and analytical tools with the objective of protecting public health. The first study introduces an agent-based simulation platform that serves ... -
Building a systematic analytic pipeline – big data innovation in healthcare
(Georgia Institute of Technology, 2019-08-27)Electronic Health Records (EHR) containing large amount of patient data present both opportunities and challenges to industry, policy makers, and researchers. Data-driven healthcare utilizing big data in EHR has the potential ... -
Biochemical Characterization and Cryo-EM Studies of a Highly Active Spinach Photosystem II Complex
(Georgia Institute of Technology, 2018-11-13)Photosystem II (PSII) is a large, photosynthetic membrane protein complex responsible for water oxidation and the formation of oxygen on Earth. Understanding the structure of this protein is important for studying ... -
Characterization of Primary Rat Astrocytes: a Step Towards Optic Nerve Head on a Chip
The mechanism by which elevated intraocular pressure (IOP) increases risk of glaucoma remains unknown. A proposed pathway suggests astrocytes sense optic nerve head (ONH) deformation due to increased IOP, triggering their ... -
Competition Dynamics between Ancestral Unicellular and Laboratory-Evolved Multicellular Chlamydomonas reinhardtii
Life on Earth as humanity comprehends it would be unthinkable without multicellular organisms. Despite the pervasiveness of multicellularity, the mechanisms of its evolutionary origin remain largely a mystery. Fortunately, ... -
Variation in Coral Microbiome Composition and Transcriptional Activity of Three Corals over Diel Cycles
Understanding the dynamics of coral microbiome composition and function is important because microbiomes play important roles in coral health and metabolism. While numerous long-term studies have investigated changes in ... -
Investigating Biomarkers for Antidepressant Efficacy via Cognitive Behavioral Assessment and fMRI
Although many treatment options have been developed to treat Major Depressive Disorder, the efficacy of these treatment options remain limited. Past studies on antidepressant efficacy have identified a range of cognitive ... -
Development of an Assay for Sphingomyelinase D Products in Venom from Loxosceles reclusa and Other Spiders
The venoms of Loxosceles reclusa, the brown recluse spider, and some other Loxosceles species cause dermonecrotic lesions—a dying of the flesh—and in severe cases, systemic injury and death. Since this type of injury results ... -
Testing how methods impact the results of interspecific competition research
There are currently two methods that can be used to measure interspecific competition, pairwise and mutual invasion. Both can be used to generate niche difference (ND) and relative fitness difference (RFD) values, as well ... -
Using Polymorphic Microsatellites to Determine the Population Genetics of Vespula maculifrons
Social insects have an interesting genetic history and are studied in order to discern how their social behaviors affects their genetic makeup. The eastern yellowjacket Vespula maculifrons is one such species whose altruistic ... -
Expanding test methods for marine ecotoxicology testing using Proales similis
This study is the first inquiry into the suitability of the rotifer Proales similis as a test animal for researchers studying marine pollution. It also introduces a novel toxicity test based on inhibition of hatching ... -
Analysis of metastatic-repressing microRNAs and determining ZEB1 as a gene candidate for siRNA knockout in mesenchymal-like ovarian and prostate cancer cell lines
MicroRNAs (miRNAs) have been shown to play a significant role in cancer progression and metastasis through their regulation of gene expression to activate epithelial-mesenchymal transition (EMT). Understanding the genetic ... -
Uncovering the peatland root microbiome: Environmental factors shaping microbial community structure
This study examines the effects of simulated whole-ecosystem warming and elevated levels of carbon dioxide on the microbial communities within the root-soil microbiomes of vascular plants in peatlands. Root samples ... -
Quasi-Periodic Patterns of Resting-State Brain Activity in Individuals with Idiopathic Hypersomnia and Narcolepsy
The brain’s overall organization of its networks is often studied through its functional connectivity, defined as the spatiotemporal dependency of neuronal activity in anatomically separated regions. Altered functional ... -
Single Cell Analysis of Patients with Perianal Chron’s Disease
Perianal Chron’s Disease is a debilitating form of Chron’s Disease that often involves rectal tissue in its manifestation in the body. There is a greater need for understanding of the role of the epithelial tissue in the ...
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