• Hsp90 and the Evolution of Novel Cellular Differentiation 

  Cheng, Vivian

  Cellular differentiation is a prerequisite for complex multicellular life, yet little is known about how it evolves de novo. Several mechanisms may explain how early multicellular organisms evolved to perform cell-specific ...

• The True Cost: An Analysis of Course Registration Patterns in the College of Sciences 

  Ciaccia, Julia

  In the United States, less than half of college students who enroll in a STEM program will graduate with a STEM degree (Chen 2013). Attrition rates are disproportionately high for marginalized students, leading to a ...

• Prediction and Visualization of RNA Secondary Structures 

  McCann, Holly

  Non-coding RNAs play key roles in cellular systems such as transcription and translation. Computational predictive methods provide insight into the secondary structures of non-coding RNAs from diverse organisms for which ...

• Metagenomic evaluation of the caddisfly-associated microbiome and its implications for nutrient cycling in montane streams 

  Pryor, Chloe

  Anthropogenic excess nitrogen in the environment has many negative impacts on environmental and human health, including eutrophication, pollution, and loss of biodiversity. River systems carry the burden of regulating this ...

• Analysis of Tympanum and Columella Constructions in the Family Incilius (Anura: Bufonidae: Incilius) 

  Shinn, Ollie

  Toad ears are usually composed of a tympanic membrane, tympanic annulus, columella, and inner ear, and vary greatly across species. In order to investigate the state and evolutionary history of ears within the toad family ...

• Effects of Muscle-Based Control and Electrical Stimulation of Residual Sensory Nerve on Biomechanics of Locomotion with Transtibial Prosthesis 

  Zhang, Celina

  This study examines the use of muscle activity and nerve stimulation for trans-tibial prosthetic control. We tested various modes of an osseointegrated prosthesis – in a cat subject – that varied in their implementation ...

• Interaction between Burkholderia ceoncepacia and Staphylococcus aureus in Presence of Meropenem 

  Wang, Runyi

  In recent decades, chronic pulmonary infections have become the leading cause of death among patients with cystic fibrosis. Despite the large number of available studies that explore the effects of single-species bacterial ...

• Reproduction and recruitment in perennial Vespula squamosa yellowjacket was colonies 

  Crossley, Henry G.

  Many people are all too familiar with social wasps of the genus Vespula, more commonly known as yellowjackets. What many people may not know is that recently, the nesting behavior of these wasps has begun to shift from a ...

• Modeling health and developmental effects of particulate matter exposure using C. elegans 

  Thompson, Carys

  Particulate matter (PM) is air pollution comprised of tiny particles suspended in the air. Exposure to PM is a major global health concern, contributing to 9 million deaths annually. Fine PM can break down protective ...

• Single-cell RNA Sequencing Analysis and Experimental Designs to Investigate the Role of Nitric Oxide Signaling in Progenitor Cell Survival in Ciona 

  Gurgis, Alexandra Marie

  The tunicate Ciona is a marine chordate whose biphasic life cycle, relatively simple transcriptome, and ability to be genetically manipulated via electroporation makes it an ideal model for studying phenomena of neurodevelopment ...

• A preliminary investigation into the role of Sipa1l in bipolar tail neurons of Ciona robusta 

  Shearer, Tanner Reid

  Bipolar tail neurons (BTNs) in Ciona robusta offer a unique chance to assess regulatory networks that give rise to cell behaviors during development. Like most cells within the embryo of Ciona robusta, BTNs develop following ...

• Purification of N-glycosylated E-Cadherin Proteins through Biotinylation Isolation of E-cadherin protein for glycomics study through biotin affinity purification 

  Patel, Roshni R.

  In this study, we use Xenopus embryos to study the dynamics of neural crest cell migration. This process is important in embryonic development because it initiates the differentiation process of the embryo as a whole. The ...

• Analysis of Neural Stem Cells and Neurospheres 

  Palanivel, Shivani

  Neural stem cells (NSCs) are important multipotent adult stem cells capable of self-renewal and differentiation into various cell types present in the central nervous system. Studying the characteristics of NSCs and their ...

• Neuroprotective Effects of Voluntary Exercise in a Mouse Model of Retinitis Pigmentosa 

  Karesh, Austin

  Aerobic exercise is a promising rehabilitation intervention for the central and peripheral nervous systems. We previously reported neuroprotective effects of voluntary exercise in inherited and acute damage animal models ...

• A Novel Approach to Restore Proprioceptive Feedback Following Spinal Cord Injuries Using Eccentric Training 

  McMurtry, Shea (Georgia Institute of Technology, 2022-05-03)

  Incomplete spinal cord injuries (SCI) lead to a variety of motor deficits including problems with ambulation. A further understanding of the pathophysiology leading to these deficits is required to develop therapies. ...

• Clinical utility of targeted RNAseq in neuromuscular and immune disorders 

  Berger, Kiera (Georgia Institute of Technology, 2022-05-02)

  A specific genetic diagnosis leads to lower health care costs and improvement in clinical outcomes for rare congenital diseases. Despite significant advancements in sequencing technology and bioinformatic analysis, only ...

• COMBINING HUERISTIC APPROACHES WITH MACHINE LEARNING TO RECOMMEND POST TRANSLATIONAL MODIFICATIONS FOR STUDY 

  English, Nolan (Georgia Institute of Technology, 2022-04-28)

  Post-translational modifications (PTMs) alter the chemistry of amino acid residues within translated proteins and thereby have the potential to expand the function and complexity of the proteome beyond the limits of the ...

• The genetics and epigenetics of plasticity in social insects 

  Dyson, Carl J. (Georgia Institute of Technology, 2022-04-26)

  Highly social (eusocial) insects, in particular, comprise some of the most successful species on Earth due in large part to their high levels of cooperation and division of labor. However, these behaviors are subject to ...

• Genetic and Environmental Factors Influencing the Genomic Prediction of Complex Traits 

  Nagpal, Sini (Georgia Institute of Technology, 2022-04-19)

  Precision medicine is an emerging field in health care which aims to synthesize therapeutics precisely targeted towards a subgroup of individuals identified to be at a higher risk of a disease. The subgroups of individuals ...

• UNDERSTANDING THE ROLE MAS-RELATED G PROTEIN-COUPLED RECEPTORS PLAY IN MEDIATING ITCH SENSATION 

  Steele, Haley Rae (Georgia Institute of Technology, 2022-04-14)

  Although chronic itch is the most common reason for visiting the dermatologist, there remain few effective treatments. Glabrous skin itch, which occurs on the palms of hands and soles of feet, is extremely debilitating. ...

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