Now showing items 1-10 of 11
Repair, consequence, and profile of ribonucleotides in DNA
(Georgia Institute of Technology, 2015-03-12)
Ribonucleotides, also known as ribonucleoside monophosphates (rNMPs), are the most abundant non-canonical nucleotides incorporated into genomic DNA. Despite the relevance, information about their repair pathways, consequences, ...
An investigation of inherently curved DNA in the upstream activator sequence (UAS) of E coli rrnB P1 promoter
(Georgia Institute of Technology, 1989-08)
Catabolite activator protein induced bending studied by covalent circularization of short DNA fragment
(Georgia Institute of Technology, 1985-12)
Triple helix formation between a short DNA hairpin molecule and linear single stranded oligonucleotides
(Georgia Institute of Technology, 1995-08)
Algorithm development for next generation sequencing-based metagenome analysis
(Georgia Institute of Technology, 2010-08-26)
We present research on the design, development and application of algorithms for DNA sequence analysis, with a focus on environmental DNA (metagenomes). We present an overview and primer on algorithm development for ...
Effects of repetitive DNA and epigenetics on human genome regulation
(Georgia Institute of Technology, 2013-07-02)
The highly developed and specialized anatomical and physiological characteristics observed for eukaryotes in general and mammals in particular are underwritten by an elaborate and intricate process of genome regulation. ...
DNA curvature and fluctuational base pair opening in the promoter regions of escherichia coli
(Georgia Institute of Technology, 1988-12)
An investigation of cyclic AMP receptor protein (CRP)-Induced DNA bending at the lac, gal and malT operons
(Georgia Institute of Technology, 1991-08)
Comparative analysis of apoptotic function between humans, chimpanzees and macaques
(Georgia Institute of Technology, 2011-07-07)
Humans and chimpanzees differ in a number of phenotypic traits chief among them being a larger sized human brain and an increased propensity for cancer in humans. Apoptosis or programmed cell death plays a role during brain ...
Studies on the mechanisms of RNA-driven DNA repair and modification
(Georgia Institute of Technology, 2011-11-14)
Our previous studies have demonstrated that RNA can serve as a template for double-strand break (DSB) repair in the yeast Saccharomyces cerevisiae using synthetic RNA-containing oligonucleotides (oligos). Following this ...