Development of quantitative structure-activity relationship for prediction of biological effects of nanoparticles associated with semiconductor industries

Abstract

Our work aims at development of fundamental understanding of cytotoxicity of semiconductor NPs to human health and provides a comprehensive database and clear definition of ESH-problematic manufactured nanomaterials. Based on the quantitative structure-activity relationship (QSAR) model we plan to establish, problematic nanomateirals from industrial manufacturers could be predicted, identified, and effectively modified to produce environmental benign semiconductor nanomaterials.