Show simple item record

dc.contributor.authorStryker, Michael P.
dc.date.accessioned2019-12-02T19:00:15Z
dc.date.available2019-12-02T19:00:15Z
dc.date.issued2019-11-18
dc.identifier.urihttp://hdl.handle.net/1853/62070
dc.descriptionPresented on November 18, 2019 at 11:15 a.m. in the Krone Engineered Biosystems Building, Room 1005.en_US
dc.descriptionMichael Stryker is a Professor in the School of Medicine at the University of California, San Francisco. His laboratory studies the development and plasticity of the central visual system. Most of his laboratory's effort focuses on the role of neural activity in the primary visual cortex of the mouse, where they have identified a circuit that dramatically enhances activity-dependent plasticity in adult animals.en_US
dc.descriptionRuntime: 64:40 minutesen_US
dc.description.abstractMichael Stryker's laboratory studies the development and plasticity of the central visual system. Most of his laboratory's effort focuses on the role of neural activity in the primary visual cortex of the mouse, where they have identified a circuit that dramatically enhances activity-dependent plasticity in adult animals. They use 2-photon microscopy and electrophysiology to study genetically identified types of neurons in alert animals. His laboratory's major interest is the in the mechanisms responsible for the development and plasticity of precise connections within the central nervous system, and particularly in the role of neural activity in this process. Most of the work performed is on the visual cortex of the mouse. In normal development, neural connections to and within the visual cortex are refined to high precision through the action of activity-dependent mechanisms of neural plasticity in combination with specific molecular signals. In experiments, the lab induces activity-dependent plasticity experimentally through manipulations of genetics or experience or by pharmacological or neurophysiological intervention in order to discover what cellular mechanisms and what changes in cortical circuitry are responsible for rapid, long lasting changes in neuronal responses. These changes are analyzed using microelectrode recordings, novel techniques for measurement of optical and metabolic signals related to neural activity, including 2-photon microscopy and intrinsic signal imaging, and anatomical and neurochemical tracing of connections.en_US
dc.format.extent64:40 minutes
dc.language.isoen_USen_US
dc.relation.ispartofseriesGT Neuro Seminar Seriesen_US
dc.subjectBrain developmenten_US
dc.subjectNeural plasticityen_US
dc.subjectOcular dominanceen_US
dc.titleTwo Forms of Plasticity in Adult Visual Cortexen_US
dc.typeLectureen_US
dc.typeVideoen_US
dc.contributor.corporatenameGeorgia Institute of Technology. Neural Engineering Centeren_US
dc.contributor.corporatenameUniversity of California, San Francisco. School of Medicineen_US


Files in this item

Thumbnail
Thumbnail
Thumbnail
Thumbnail

This item appears in the following Collection(s)

Show simple item record