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    Trans-skull Ultrasound for Imaging and Therapy

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    SCHOEN-DISSERTATION-2020.pdf (93.14Mb)
    Date
    2020-12-03
    Author
    Schoen, Scott J.
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    Abstract
    Ultrasound has emerged as a novel modality for the treatment and imaging of brain diseases. When enhanced by circulating microbubble agents, which scatter sound and vibrate in response to the incident ultrasound, it can enable a range of new therapeutic interventions and open new possibilities for imaging. Despite these advancements, the skull remains a major challenge both for therapy and imaging. This work proposes methods for fast, frequency-selective passive reconstruction of the acoustic field through human skull with applications including improved targeting for exploitation of nonlinear acoustic effects in the brain, controlling the microbubble dynamics, and super-resolution imaging.
    URI
    http://hdl.handle.net/1853/64174
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    • Georgia Tech Theses and Dissertations [23403]
    • School of Mechanical Engineering Theses and Dissertations [4008]

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