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dc.contributor.authorHelmchen, Fritjof
dc.date.accessioned2021-02-23T21:19:15Z
dc.date.available2021-02-23T21:19:15Z
dc.date.issued2021-02-15
dc.identifier.urihttp://hdl.handle.net/1853/64302
dc.descriptionPresented online on February 15, 2021 at 11:15 a.m.en_US
dc.descriptionFritjof Helmchen is Professor of Neuroscience and Co-Director of the Brain Research Institute. His research is focused on the development and application of optical methods, in particular two-photon microscopy, to study neural activity on the subcellular, cellular, and circuit level. His group has pioneered several microscopy techniques, including 3D, high-speed, and multi-area in vivo two-photon imaging, and has contributed to recent advancements in the study of cortical microcircuits.
dc.descriptionRuntime: 72:52 minutes
dc.description.abstractThrough the combination of in vivo optical imaging and chronic expression of genetically encoded calcium indicators it is now feasible to directly 'watch' brain activity patterns related to specific behaviors. I will introduce wide-field calcium imaging and multi-fiber photometry as two complementary methods that enable measurements across mouse neocortex and in large sets of subcortical regions, respectively. Specific patterns of brain-wide signal flow that occur in mice performing whisker-based or auditory sensory discrimination tasks will be discussed, highlighting salient patterns related to short-term memory. In addition, taking advantage of chronic measurements over weeks, I will present salient changes in brain dynamics that relate to task learning.en_US
dc.format.extent72:52 minutes
dc.language.isoen_USen_US
dc.relation.ispartofseriesGT Neuro Seminar Series;
dc.subjectCalcium imagingen_US
dc.subjectMouseen_US
dc.subjectSensory discriminationen_US
dc.titleBrain dynamics related to short-term memory and learningen_US
dc.typeLectureen_US
dc.typeVideoen_US
dc.contributor.corporatenameGeorgia Institute of Technology. Neural Engineering Centeren_US
dc.contributor.corporatenameUniversity of Zurich. Brain Research Instituteen_US


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