• Mapping Protein Folding on Organismal Fitness One Mutation at a Time 

      Shakhnovich, Eugene (Georgia Institute of Technology, 2013-03-12)
      In this presentation I will describe our efforts at understanding how molecular properties of proteins determine fitness landscape of populations of carrier organisms. Recent multi-scale evolutionary models, which assume ...
    • Steroidogenesis-inducing protein: An enigmatic protein with multiple biological functions 

      Khan, Shafiq A. (Georgia Institute of Technology, 2008-10-09)
      SIP was isolated and characterized from human ovarian follicular fluid in our laboratory on the basis of its profound effects on steroid production in testicular, ovarian and adrenal cells. Later studies showed that SIP ...
    • Visualizing Biological Machines with CryoEM 

      Carragher, Bridget (Georgia Institute of Technology, 2008-09-22)
      Over the past decade, cryo-electron microscopy (cryoEM) has emerged as a powerful approach to the structural determination of large macromolecular complexes. Elucidating the structure and mechanism of action of these ...