Multimodal Registration of White Matter Brain Data via Optimal Mass Transport

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Title: Multimodal Registration of White Matter Brain Data via Optimal Mass Transport
Author: Rehman, Tauseef ur ; Haber, Eldad ; Pohl, Kilian M. ; Haker, Steven ; Halle, Michael ; Talos, Florin ; Wald, Lawrence L. ; Kikinis, Ron ; Tannenbaum, Allen R.
Abstract: The elastic registration of medical scans from different acquisition sequences is becoming an important topic for many research labs that would like to continue the post-processing of medical scans acquired via the new generation of high-field-strength scanners. In this note, we present a parameter-free registration algorithm that is well suited for this scenario as it requires no tuning to specific acquisition sequences. The algorithm encompasses a new numerical scheme for computing elastic registration maps based on the minimizing flow approach to optimal mass transport. The approach utilizes all of the gray-scale data in both images, and the optimal mapping from image A to image B is the inverse of the optimal mapping from B to A. Further, no landmarks need to be specified, and the minimizer of the distance functional involved is unique. We apply the algorithm to register the white matter folds of two different scans and use the results to parcellate the cortex of the target image. To the best of our knowledge, this is the first time that the optimal mass transport function has been applied to register large 3D multimodal data sets.
Type: Proceedings
Citation: Tauseef ur Rehman, Eldad Haber, Kilian M. Pohl, Steven Haker, Mike Halle, Florin Talos, Lawrence L. Wald, Ron Kikinis and Allen Tannenbaum, "Multimodal Registration of White Matter Brain Data via Optimal Mass Transport," The MIDAS Journal - Computational Biomechanics for Medicine (MICCAI 2008 Workshop) 27-36:
Date: 2008-09
Contributor: Georgia Institute of Technology. Dept. of Biomedical Engineering
Emory University. Dept. of Biomedical Engineering
Georgia Institute of Technology. School of Electrical and Computer Engineering
Emory University. Dept. of Mathematics and Computer Science
Brigham and Women’s Hospital. Dept. of Radiology. Surgical Planning Laboratory
Massachusetts General Hospital. Dept. of Radiology
Publisher: Georgia Institute of Technology
Insight Software Consortium
Subject: Optimal mass transport
Monge Kantorovich
Variational methods
Fluid mechanics

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