Cell Cycle Control

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Please use this identifier to cite or link to this item: http://hdl.handle.net/1853/34886

Title: Cell Cycle Control
Author: Nurse, Paul
Abstract: The growth and reproduction of all living organisms are dependent on the cell cycle, the process which leads to cell division. Uncontrolled division of cells is important for disease particularly cancer. Two events, S-phase and mitosis, are common to all cell cycles and are necessary for the two newly divided cells to receive a full complement of genes. In fission yeast the onset of S-phase and mitosis are controlled by a single cyclin dependent kinase with different levels of CDK activity bringing about progression through the cell cycle in an ordered fashion. Activation of CDK activity is determined by growth rate and cell size, with cell size determined by a gradient mechanism with controlling molecules diffusing from the periphery of the cell to be sensed in the middle of the cell.
Description: Dr. Paul Nurse, 2001 Nobel prize winner in medicine and President, The Rockefeller University, presented a lecture at 11:00 AM, Wednesday, September 8, 2010 in the Marcus Nanotechnology building, Room 1116. Runtime: 51:04 minutes
Type: Lecture
Video
URI: http://hdl.handle.net/1853/34886
Date: 2010-09-08
Contributor: Rockefeller University
Georgia Institute of Technology. Integrative BioSystems Institute
Publisher: Georgia Institute of Technology
Subject: Cell cycle
S-phase
Mitosis
CDK activity
Cyclin-dependent kinase
Biology

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