Complete genome sequence of Candidatus Ruthia magnifica

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Title: Complete genome sequence of Candidatus Ruthia magnifica
Author: Roeselers, Guus ; Newton, Irene L. G. ; Woyke, Tanja ; Dilly, Geoffrey F. ; Meredith C. Fisher ; Lau, Evan ; Richardson, Paul M. ; Saunders, Elizabeth ; Wu, Dongying ; Cavanaugh, Colleen M. ; Auchtung, Thomas A. ; Dutton, Rachel J. ; Fontanez, Kristina M. ; Stewart, Frank J. ; Barry, Kerrie W. ; Detter, John C. ; Eisen, Jonathan A.
Abstract: The hydrothermal vent clam Calyptogena magnifica (Bivalvia: Mollusca) is a member of the Vesicomyidae. Species within this family form symbioses with chemosynthetic Gammapro-teobacteria. They exist in environments such as hydrothermal vents and cold seeps and have a rudimentary gut and feeding groove, indicating a large dependence on their endosymbionts for nutrition. The C. magnifica symbiont, Candidatus Ruthia magnifica, was the first intracel-lular sulfur-oxidizing endosymbiont to have its genome sequenced (Newton et al. 2007). Here we expand upon the original report and provide additional details complying with the emerging MIGS/MIMS standards. The complete genome exposed the genetic blueprint of the metabolic capabilities of the symbiont. Genes which were predicted to encode the proteins required for all the metabolic pathways typical of free-living chemoautotrophs were detected in the symbiont genome. These include major pathways including carbon fixation, sulfur oxi-dation, nitrogen assimilation, as well as amino acid and cofactor/vitamin biosynthesis. This genome sequence is invaluable in the study of these enigmatic associations and provides in-sights into the origin and evolution of autotrophic endosymbiosis.
Description: This work is licensed under a Creative Commons Attribution 3.0 License. DOI:10.4056/sigs.1103048
Type: Article
URI: http://hdl.handle.net/1853/42271
ISSN: 1944-3277
Citation: Roeselers G, Newton ILG, Woyke T, Auchtung TA, Dilly GF, Dutton RJ, Fisher MC, Fontanez KM, Lau E, Stewart FJ, Richardson P, Barry K, Saunders E, Detter JC, Wu D, Eisen JA, Cavanaugh CM. Complete genome sequence of Candidatus Ruthia magnifica. Standards in Genomic Sciences (2010) 3:163-173.
Date: 2010
Contributor: Harvard University. Dept. of Organismic and Evolutionary Biology
Radboud Universiteit Nijmegen. Dept. of Microbiology
Wellesley College. Dept. of Biological Sciences
Joint Genome Institute
United States. Dept. of Energy
Harvard Medical School. Dept. of Microbiology and Molecular Genetics
UC Davis Genome Center
Publisher: Georgia Institute of Technology
Genomic Standards Consortium
Subject: Hydrothermal vent
Clam
Sulfur
Symbiosis
Chemosynthesis
Vesicomyidae

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